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心房颤动患者直流电复律后心肌肌钙蛋白I水平变化的评估

Evaluation of Changes in Cardiac Troponin I Levels After Direct Current Cardioversion in Patients With Atrial Fibrillation.

作者信息

Katerini Marina, Politi Christine, Konstantakopoulou Olympia, Kyritsi Eleni, Minasidou Evgenia, Kourkouta Lambrini, Koukourikos Konstantinos, Tsaloglidou Areti

机构信息

Cardiology Clinic, General Hospital of Pella (Hospital Unit of Edessa), Thessaloniki, GRC.

Nursing, National and Kapodistrian University of Athens, Athens, GRC.

出版信息

Cureus. 2024 Aug 18;16(8):e67162. doi: 10.7759/cureus.67162. eCollection 2024 Aug.

Abstract

INTRODUCTION

Direct current cardioversion (DCCV) of atrial fibrillation (AF) is a procedure used to restore normal heart rhythm. Cardiac biomarkers, such as cardiac troponin I (cTnI), are elevated in situations where injury-myocardial cell necrosis is induced.

AIM

The aim of the present study was to investigate the change in cTnI levels, i.e., whether a myocardial injury is present, in patients with AF whose elective treatment was synchronized DCCV via a biphasic defibrillator.

METHODS

The study sample included 59 patients who underwent synchronized DCCV for AF reversion. Measurement of cTnI before and after DCCV (one, three, and six hours) was performed by blood sampling and subsequent assay.

RESULTS

It was observed that the value of cTnI did not change (<0.1 ng/mL) after DCCV at the measurement time points (one, three, and six hours). In addition, the value of cTnI remained constant (<0.1 ng/mL) in relation to the energy delivered, before DCCV and after DCCV (one, three, and six hours). However, it was found that there was a correlation between the outcome (AF reversion or not) and the energy used (joules).

CONCLUSIONS

Synchronized DCCV with a biphasic defibrillator did not cause myocardial injury in any of the patients, as there was no change in cTnI values before and after DCCV.

摘要

引言

心房颤动(AF)的直流电复律(DCCV)是一种用于恢复正常心律的操作。在诱导损伤 - 心肌细胞坏死的情况下,心脏生物标志物如心肌肌钙蛋白I(cTnI)会升高。

目的

本研究的目的是调查接受双相除颤器同步DCCV进行择期治疗的AF患者中cTnI水平的变化,即是否存在心肌损伤。

方法

研究样本包括59例接受同步DCCV以恢复AF的患者。通过采血和随后的检测在DCCV之前和之后(1小时、3小时和6小时)测量cTnI。

结果

观察到在测量时间点(1小时、3小时和6小时)DCCV后cTnI值未发生变化(<0.1 ng/mL)。此外,相对于传递的能量,在DCCV之前和之后(1小时、3小时和6小时)cTnI值保持恒定(<0.1 ng/mL)。然而,发现结果(AF是否恢复)与所使用的能量(焦耳)之间存在相关性。

结论

双相除颤器同步DCCV在任何患者中均未引起心肌损伤,因为DCCV前后cTnI值没有变化。

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