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复杂神经后遗症:一名年轻患者新冠病毒感染后出现轴索性吉兰-巴雷综合征

Complex Neurological Sequelae: Axonal Guillain-Barré Syndrome Post COVID-19 in a Young Patient.

作者信息

Umar Anam, Faquih Amber E, Jawed Bilal, Bilal Muhammad

机构信息

Internal Medicine, Ascension St. Vincent's Birmingham, Birmingham, USA.

Infectious Diseases, University of Alabama at Birmingham, Birmingham, USA.

出版信息

Cureus. 2024 Aug 19;16(8):e67213. doi: 10.7759/cureus.67213. eCollection 2024 Aug.

Abstract

Guillain-Barré syndrome (GBS) encompasses a spectrum of immune-mediated neuropathies, with axonal GBS representing a less common yet often severe subtype. This variant directly damages peripheral nerve axons, resulting in rapid and profound muscle weakness and sensory deficits. Axonal GBS has similar clinical features to the demyelinating form but is generally more severe with a less favorable prognosis. Here, we present a case of axonal GBS in a 46-year-old female following a mild COVID-19 infection, highlighting the diagnostic challenges and the importance of tailored therapeutic approaches and multidisciplinary care in managing this condition.

摘要

吉兰-巴雷综合征(GBS)涵盖一系列免疫介导的神经病变,其中轴索性吉兰-巴雷综合征是一种较罕见但通常较为严重的亚型。这种变异型直接损害周围神经轴突,导致迅速且严重的肌肉无力和感觉障碍。轴索性吉兰-巴雷综合征具有与脱髓鞘型相似的临床特征,但通常更为严重,预后较差。在此,我们报告一例46岁女性在轻度新型冠状病毒肺炎感染后发生轴索性吉兰-巴雷综合征的病例,强调了诊断挑战以及在管理该疾病时采取个性化治疗方法和多学科护理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed4/11410110/d0693aafdd3c/cureus-0016-00000067213-i01.jpg

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