Beaulieu Carissa, Wu Kai Yi, Füzéry Anna K, Raizman Joshua E, Tsui Albert K Y, Ye Carrie, Basappa Naveen S, Gyenes Gabor T, Koshman Sheri L
Division of Medical Oncology, Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada.
Division of Cardiology, Department of Medicine, University of Alberta, Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada.
JACC Case Rep. 2024 Aug 21;29(16):102462. doi: 10.1016/j.jaccas.2024.102462.
A patient with metastatic renal cell carcinoma on axitinib and pembrolizumab had elevated high-sensitivity cardiac troponin T and normal high-sensitivity cardiac troponin I with unremarkable cardiac investigations. A noncardiac cause (myositis) was the likely cause for cardiac troponin T elevation. Cardiac troponin I may be a more appropriate marker to support a myocarditis diagnosis with concurrent myositis.
一名接受阿昔替尼和派姆单抗治疗的转移性肾细胞癌患者，其高敏心肌肌钙蛋白T升高，高敏心肌肌钙蛋白I正常，心脏检查无异常。非心脏原因（肌炎）可能是心肌肌钙蛋白T升高的原因。在合并肌炎的情况下，心肌肌钙蛋白I可能是支持心肌炎诊断的更合适标志物。
