Hong Liang Ong, Ee Meng Cheng, Mohamad Che Wan Sharifah Robiah, Mohd Nasir Nashrul Fazli, Xiao Jian Tan, Chong You Beh, Ziezie Mohd Tarmizi Emma, Kim Yee Lee, Kok Yeow You, Shing Fhan Khor, Kim Fey Leu, Kian Keong Te, Mohd Roslan Mohd Riza, Baharuddin Siti Aishah
Faculty of Electronic Engineering & Technology, Universiti Malaysia Perlis (UniMAP), Perlis, 02600, Malaysia.
Advanced Communication Engineering (ACE) Centre of Excellence, Universiti Malaysia Perlis (UniMAP), Perlis, 02600, Malaysia.
Heliyon. 2024 Aug 28;10(17):e37077. doi: 10.1016/j.heliyon.2024.e37077. eCollection 2024 Sep 15.
Radix Glycyrrhizae, the dried roots of the Glycyrrhiza glabra plant, is a popular Chinese herbal medicine known for its various health benefits. It is particularly effective in relieving respiratory problems like coughs, sore throats, bronchitis, and asthma. However, there is limited research on the electrical properties of Radix Glycyrrhizae, likely due to its complex composition of phytochemical and antioxidant activities. This research aims to investigate the potential of these active biological compounds and understand their electrochemical properties. In this study, High-Performance Liquid Chromatography (HPLC) analysis revealed that Radix Glycyrrhizae decoction contains significant amounts of flavonoids and saponins, compounds known for their health benefits and therapeutic effects. Further analysis using Fourier Transform Infrared Spectroscopy (FTIR) identified several functional groups, including phenols, alcohols, alkynes, alkenes, ethers, and glycosides, which contribute to the plant's medicinal potential and affect the impedance and dielectric properties of the extract. The antioxidant activity of Radix Glycyrrhizae decoction was also evaluated using DPPH assays, showing similar radical scavenging activity to gallic acid. Dielectric and impedance measurement of Radix Glycyrrhizae extract were performed using an Agilent vector network analyzer and a Hioki impedance analyzer. The dielectric constant measured was consistent across both analyzers. However, the loss factor showed different trends: the vector network analyzer indicated a decrease in the loss factor with increasing frequency in the range of 5 MHz-20 GHz, while the impedance analyzer showed the opposite trend in the frequency range of 4 Hz-5 MHz.
甘草根，即光果甘草植物的干燥根，是一种广为人知的具有多种健康益处的中国草药。它在缓解咳嗽、喉咙痛、支气管炎和哮喘等呼吸道问题方面特别有效。然而，关于甘草根电学性质的研究有限，这可能是由于其复杂的植物化学成分和抗氧化活性。本研究旨在探究这些活性生物化合物的潜力，并了解它们的电化学性质。在本研究中，高效液相色谱（HPLC）分析表明，甘草根汤剂含有大量黄酮类化合物和皂苷，这些化合物以其健康益处和治疗效果而闻名。使用傅里叶变换红外光谱（FTIR）进行的进一步分析确定了几个官能团，包括酚类、醇类、炔类、烯烃类、醚类和糖苷类，这些官能团有助于植物的药用潜力，并影响提取物的阻抗和介电性能。还使用DPPH测定法评估了甘草根汤剂的抗氧化活性，结果表明其自由基清除活性与没食子酸相似。使用安捷伦矢量网络分析仪和日置阻抗分析仪对甘草根提取物进行了介电和阻抗测量。两台分析仪测得的介电常数一致。然而，损耗因子呈现出不同的趋势：矢量网络分析仪表明，在5 MHz - 20 GHz范围内，损耗因子随频率增加而降低，而阻抗分析仪在4 Hz - 5 MHz频率范围内呈现相反的趋势。
