Department of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, Azad Kashmir 13230, Pakistan.
Molecules. 2020 Nov 11;25(22):5243. doi: 10.3390/molecules25225243.
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.
类黄酮是存在于许多植物、水果、蔬菜和叶子中的植物化学化合物，在药用化学中有潜在的应用。类黄酮具有许多药用益处，包括抗癌、抗氧化、抗炎和抗病毒特性。它们还具有神经保护和心脏保护作用。这些生物活性取决于类黄酮的类型、其（可能的）作用模式和生物利用度。这些具有成本效益的药用成分具有显著的生物活性，其有效性已在各种疾病中得到证实。最近的工作重点是使用各种技术和动物模型对其进行分离、类似物的合成及其对人类健康的影响。已经成功分离出数千种类黄酮，而且这个数字还在稳步增加。因此，我们努力总结了具有有用活性的分离类黄酮，以便更好地了解它们对人类健康的影响。
