Jiang Fengli, Chen Qi, Wu Yuanyuan, Lin Jinhao, Su Xueshang, Zhuang Jun, Zhan Sien
From the Department of Medical Laboratory, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Clinical Medicine, Xinjiang Medical University, Xinjiang, China.
Plast Reconstr Surg Glob Open. 2024 Sep 18;12(9):e6165. doi: 10.1097/GOX.0000000000006165. eCollection 2024 Sep.
We aimed to summarize the distribution of pathogenic bacteria for postoperative infection of different genitourinary plastic surgery and the antimicrobial resistance of the major pathogens.
Between January 2011 and December 2021, following plastic surgery of the urogenital system, microbial strains from infected patients were collected, identified, and counted. The antibiotic sensitivity and distribution characteristics of common pathogens in relation with the surgical procedures were studied by WHONET 5.6, along with the main bacteria accounting for early infection.
A total of 76 cases were included in the study. Among these, 53 Gram-negative bacteria were detected, with (18 of 53) and (nine of 53) accounting for the majority. There were also 23 Gram-positive bacteria, among which (six of 23) and Coagulase-negative (five of 23) were the most common. In terms of antimicrobial resistance, was highly sensitive to amikacin, piperacillin/tazobactam, cefoxitin, and imipenem, whereas was highly sensitive to gentamicin, amikacin, cefepime, piperacillin/tazobactam, imipenem, ceftazidime, and ciprofloxacin. Procedures for urethral repair, urethral reconstruction, and lump resection were most commonly associated with infection. Among these, urethral repair was responsible for the majority of infections. The pathogenic bacteria involved in postoperative infections varied overall, but the most prevalent was .
Gram-negative bacteria are the major cause of infection following genitourinary plastic surgery. The specific bacterial strains, degrees of antimicrobial resistance, and length of infection varied among the various procedures. The results of this study may provide references for clinical medication and the prevention and control of such infections.
我们旨在总结不同泌尿生殖系统整形手术后感染的病原菌分布情况以及主要病原菌的耐药性。
2011年1月至2021年12月期间，收集泌尿生殖系统整形手术后感染患者的微生物菌株，进行鉴定和计数。使用WHONET 5.6研究常见病原菌的药敏情况及其与手术方式相关的分布特征，以及导致早期感染的主要细菌。
本研究共纳入76例病例。其中，检测到53株革兰阴性菌，其中大肠埃希菌（53株中的18株）和肺炎克雷伯菌（53株中的9株）占多数。还检测到23株革兰阳性菌，其中金黄色葡萄球菌（23株中的6株）和凝固酶阴性葡萄球菌（23株中的5株）最为常见。在耐药性方面，大肠埃希菌对阿米卡星、哌拉西林/他唑巴坦、头孢西丁和亚胺培南高度敏感，而肺炎克雷伯菌对庆大霉素、阿米卡星、头孢吡肟、哌拉西林/他唑巴坦、亚胺培南、头孢他啶和环丙沙星高度敏感。尿道修复、尿道重建和肿块切除术最常与感染相关。其中，尿道修复导致的感染占多数。术后感染所涉及的病原菌总体有所不同，但最常见的是大肠埃希菌。
革兰阴性菌是泌尿生殖系统整形手术后感染的主要原因。不同手术方式中具体的细菌菌株、耐药程度和感染时长各不相同。本研究结果可为临床用药及此类感染的预防和控制提供参考。
