Al-Obaidi Hasan, Moliya Pratiksha, Al-Obaidi Ahmed Dheyaa, Harb Hussein, Al-Badri Sajjad Ghanim, Hashim Hashim Talib, Agha Iya, Mora Maximo, Merza Nooraldin, Othman Assalah, Patel Avani
Department of Medicine, Jamaica Hospital Medical Center, New York City, NY, USA.
Department of Internal Medicine, University of Baghdad, College of Medicine, Baghdad, Iraq.
Radiol Case Rep. 2024 Sep 6;19(12):5595-5599. doi: 10.1016/j.radcr.2024.08.034. eCollection 2024 Dec.
Small cell carcinomas are very aggressive malignancies that are most often linked with lung cancer, although they may also develop in the pancreas, colon, rectum, skin, and cervix. SCC of the pancreas accounts for about 1% of these neoplasms. An 88-year-old male with several comorbidities who presented with significant weight loss was diagnosed with metastatic pancreatic neuroendocrine carcinoma after complaining of persistent epistaxis and back pain. This case underscores the significance of using atypical tumor markers, such as thyroid transcription factor 1, to diagnose small-cell pancreatic cancer. It also emphasizes the importance of a multidisciplinary, patient-centered approach to managing these aggressive tumors.
小细胞癌是极具侵袭性的恶性肿瘤，最常与肺癌相关，不过也可能发生于胰腺、结肠、直肠、皮肤和子宫颈。胰腺小细胞癌约占这些肿瘤的1%。一名88岁、患有多种合并症且体重显著减轻的男性，在主诉持续鼻出血和背痛后，被诊断为转移性胰腺神经内分泌癌。该病例强调了使用非典型肿瘤标志物（如甲状腺转录因子1）诊断小细胞胰腺癌的重要性。它还强调了采用多学科、以患者为中心的方法来管理这些侵袭性肿瘤的重要性。
