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双重麻烦:胰腺同步性小细胞癌和腺癌——病例报告

Double Trouble: Synchronous Small Cell Carcinoma and Adenocarcinoma of the Pancreas - Case Report.

作者信息

Thomas Raj Jessica, Zeineddine Mohammad, Chatterjee Arjun, Cruise Michael, Krishnamurthi Smitha, Chahal Prabhleen

机构信息

Department of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USA.

Department of Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, OH, USA.

出版信息

Case Rep Oncol. 2025 May 14;18(1):653-658. doi: 10.1159/000545467. eCollection 2025 Jan-Dec.

Abstract

INTRODUCTION

Simultaneous presentation of primary tumors involving one isolated organ is few and far between. Pancreatic small cell carcinoma is unique, and it is rare to have both adenocarcinoma and small cell carcinoma present in unison within the pancreas.

CASE PRESENTATION

Presented is a 61-year-old male who was found to have synchronous small cell carcinoma and adenocarcinoma of the pancreas confirmed by endoscopic ultrasound-guided fine needle biopsy.

CONCLUSION

This case stands as a reminder that synchronous pancreatic cancer is a rarity and possibility of multiple primary malignant tumors of different origins ought to be considered when multiple tumors are present within the pancreas.

摘要

引言

一个孤立器官同时出现原发性肿瘤的情况极为罕见。胰腺小细胞癌很独特,胰腺内同时存在腺癌和小细胞癌的情况十分罕见。

病例介绍

本文报告一名61岁男性,经内镜超声引导下细针穿刺活检确诊为胰腺同步性小细胞癌和腺癌。

结论

该病例提醒我们,同步性胰腺癌很罕见,当胰腺内出现多个肿瘤时,应考虑不同起源的多个原发性恶性肿瘤的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e44/12140606/328b1a313d30/cro-2025-0018-0001-545467_F01.jpg

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