Meena Satya Prakash, Bishnoi Sumit, Badkur Mayank, Lodha Mahendra, Vishnoi Jeewan Ram, Sharma Naveen
Department of General Surgery, All India Institute of Medical Sciences Jodhpur, Rajasthan, India.
Department of Surgical Oncology, All India Institute of Medical Sciences Jodhpur, Rajasthan, India.
J Educ Health Promot. 2024 Jul 11;13:240. doi: 10.4103/jehp.jehp_47_24. eCollection 2024.
Seroma formation is a common adverse event following modified radical mastectomy, and it leads to delayed wound healing and increased post-operative pain and increases overall morbidity of patients. The quilting sutures as a newer technique for the skin flap closure is done to reduce incidence of seroma formation. Although it has controversy in the literature for the satisfactory outcome, the study has aimed to compare the Quilting suture technique with the conventional closure method to evaluate the efficacy of the quilting technique. The primary objective of the study was to access and compare the frequency of seroma formation following the quilting suture technique with standard flap closure in MRM. The secondary objectives were to compare drain output, post-operative complications, and the requirement of additional procedures for management of related complications. The 72 female participants in this randomized control trial had modified radical mastectomy after being diagnosed with breast cancer. The quilting suture technique was applied in the 36 patients and conventional technique applied in 36 patients for skin flap closure. The frequency of seroma formation and other complications were reported. Between the two groups, there was no statistically significant difference in the frequency of seroma production (P = 0.233). Total drainage volume (P = 0.213), drainage duration (P = 0.652), and post-operative complications (P = 0.641) did not substantially differ between the two groups. The study concludes that the quilting sutures technique does not decrease the incidence of seroma formation, total drain output, and total duration of drainage. There is no significant difference in complications and requirement of additional procedures compared to the standard technique.
血清肿形成是改良根治性乳房切除术后常见的不良事件，它会导致伤口愈合延迟、术后疼痛加剧，并增加患者的总体发病率。褥式缝合作为一种用于皮瓣闭合的新技术，旨在降低血清肿形成的发生率。尽管该技术在文献中对于其满意效果存在争议，但本研究旨在比较褥式缝合技术与传统闭合方法，以评估褥式缝合技术的疗效。本研究的主要目的是评估并比较在改良根治性乳房切除术中使用褥式缝合技术与标准皮瓣闭合术后血清肿形成的频率。次要目的是比较引流量、术后并发症以及处理相关并发症所需额外操作的情况。在这项随机对照试验中，72名被诊断为乳腺癌的女性参与者接受了改良根治性乳房切除术。36例患者采用褥式缝合技术进行皮瓣闭合，36例患者采用传统技术。报告了血清肿形成及其他并发症的发生频率。两组之间，血清肿产生频率无统计学显著差异（P = 0.233）。两组之间的总引流量（P = 0.213）、引流持续时间（P = 0.652）和术后并发症（P = 0.641）也无显著差异。该研究得出结论，褥式缝合技术并不能降低血清肿形成的发生率、总引流量和总引流持续时间。与标准技术相比，在并发症和额外操作需求方面没有显著差异。
