Department of Society and Health, Faculty of Social Sciences and Humanities, Mahidol University, Nakhon Pathom, Thailand.
Nakhon Phanom Hospital, Nakhon Phanom, Thailand.
PLoS One. 2024 Sep 19;19(9):e0310761. doi: 10.1371/journal.pone.0310761. eCollection 2024.
Healthcare workers (HCWs) are an important target group for influenza vaccination due to their increased risk of infection. However, their uptake remains a challenge. This study aimed to identify and measure influenza vaccine hesitancy among HCWs in Nakhon Phanom province, Thailand.
A representative cross-sectional survey was conducted during August-September 2020, among 350 HCWs at six hospitals in the province selected by a two-stage cluster sampling using a self-administered questionnaire. HCWs who either delayed getting influenza vaccines, accepted the vaccines but were unsure, or refused the vaccine with doubts were categorized as hesitant. HCWs who accepted the influenza vaccine without any doubts were classified as non-hesitant. Determinants of vaccine hesitancy were identified by a multivariable logistic regression analysis.
A total of 338 participants (97%) filled the questionnaires. The mean age of the participants was 37.2 years. Most participants were female (280; 83%), nurses (136; 40%), working at district hospitals (238; 71%), with bachelor's degree (223; 66%), and without any pre-existing chronic medical conditions (264; 78%). Influenza vaccine hesitancy was evident among nearly 60% of the participants (197/338), who had varying patterns of hesitancy. Significant factors of influenza vaccine hesitancy were found to be age above 50 years (adjusted odds ratio [aOR] 3.2, 95% CI 1.3-8.5), fair knowledge of influenza and vaccination (aOR 0.4, 95% CI 0.2-0.8), and negative influence of other HCW (High level-aOR 2.3, 95% CI 1.1-4.8; Moderate level- aOR 2.1, 95% CI 1.1-4.4).
Influenza vaccine hesitancy was highly prevalent among the Thai HCWs in Nakhon Phanom province. Imparting updated information to the HCW, in combination with positive guidance from influential HCWs in the hospital, may help reduce hesitancy. These data may be useful to the National Immunization Program to design appropriate approaches to target hesitant HCWs in Thailand to improve influenza vaccine coverage.
医护人员（HCWs）由于感染风险增加，是流感疫苗接种的重要目标人群。然而，他们的接种率仍然是一个挑战。本研究旨在确定并衡量泰国那空帕农府 HCWs 中的流感疫苗犹豫情况。
在 2020 年 8 月至 9 月期间，采用两阶段聚类抽样方法，从该省六家医院中选择了 350 名 HCWs，对他们进行了一项具有代表性的横断面调查，使用了自填式问卷。对于那些延迟接种流感疫苗、接受疫苗但不确定、或对疫苗有疑虑而拒绝接种的 HCWs，我们将其归类为犹豫者。对于那些毫不犹豫地接受流感疫苗的 HCWs，则被归类为非犹豫者。使用多变量逻辑回归分析确定了疫苗犹豫的决定因素。
共有 338 名参与者（97%）填写了问卷。参与者的平均年龄为 37.2 岁。大多数参与者为女性（280；83%）、护士（136；40%）、在区医院工作（238；71%）、拥有学士学位（223；66%），且没有任何既往慢性疾病（264；78%）。近 60%（197/338）的参与者表现出不同程度的流感疫苗犹豫，存在明显的犹豫模式。我们发现，流感疫苗犹豫的显著因素包括年龄在 50 岁以上（调整后的优势比[aOR]3.2，95%置信区间[CI]1.3-8.5）、对流感和疫苗的知识了解一般（aOR 0.4，95% CI 0.2-0.8），以及其他 HCW 的负面影响（高水平-aOR 2.3，95% CI 1.1-4.8；中水平-aOR 2.1，95% CI 1.1-4.4）。
泰国那空帕农府的 HCWs 中，流感疫苗犹豫情况非常普遍。向 HCW 提供最新信息，并结合医院内有影响力的 HCW 的积极指导，可能有助于减少犹豫。这些数据可能对国家免疫规划有用，以制定针对泰国犹豫 HCWs 的适当方法，提高流感疫苗接种率。
