Department of Emergency Services, Sunnybrook Health Science Centre, Toronto, ON, Canada; Sunnybrook Research Institute, Sunnybrook Health Science Centre, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; Division of Emergency Medicine, Department of Family and Community Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Ornge Air Ambulance and Critical Care Transport, Toronto, ON, Canada; FIRST60, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health, Toronto, ON, Canada.
Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada; Sunnybrook Centre for Prehospital Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Resuscitation. 2024 Nov;204:110381. doi: 10.1016/j.resuscitation.2024.110381. Epub 2024 Sep 18.
Ventilations are a critical component of cardiopulmonary resuscitation (CPR). There is conflicting evidence, however, on the most appropriate method of ventilation during cardiac arrest management. Recent evidence has suggested that regardless of the optimal ventilation strategy, ventilations are often not delivered compliant with guideline recommendations. Recent technological advancements have allowed for accurate measurement and real-time feedback of ventilation rate and volume during resuscitation. Simulation studies have found significant improvements in ventilations with the use of real-time feedback during simulated cardiac arrest. The use of feedback has not been studied in clinical practice. The objective of this study was to determine whether the use of real-time feedback improves compliance with pre-defined targets for ventilation rate and volume during out-of-hospital cardiac resuscitation.
This was a before-and-after study with four paramedic services in Ontario, Canada. We enrolled adult, out-of-hospital cardiac arrest (OHCA) patients where the ZOLL Accuvent® device was utilized to measure ventilation rate and volume. In the before phase (without feedback), the Accuvent® was used to measure ventilations, however, providers were blinded to the real-time feedback. In the after phase (with feedback), the feedback dashboard was activated and providers used the real-time feedback to guide their ventilations. All other aspects of resuscitation remained consistent throughout the study. The main objective of the study was to compare the proportion of each case that was compliant with pre-defined ventilation targets with real-time feedback and without real-time feedback. We also examined the use of advanced airways on ventilation quality and examined for associations between ventilation parameters and return of circulation.
We enrolled 412 patients in the study (191 in the before phase without feedback and 221 in the after phase with feedback). Overall, we found significant improvements in both ventilation rate and volume in the after phase (with real-time feedback) compared to the before phase (without real-time feedback). We did not find any differences in ventilation compliance with or without advanced airways, or intra-arrest or post-cardiac arrest.
The use of real-time feedback was associated with an increased proportion of ventilations that were compliant with pre-defined targets during cardiac resuscitation. Further work is required to improve the use of real-time ventilation feedback, and to determine the impact of ventilations on patient outcomes.
通气是心肺复苏(CPR)的一个关键组成部分。然而,关于心脏骤停管理期间最适当的通气方法,存在相互矛盾的证据。最近的证据表明,无论最佳通气策略如何,通气通常都不符合指南建议。最近的技术进步允许在复苏期间准确测量和实时反馈通气率和容量。模拟研究发现,在模拟心脏骤停期间使用实时反馈可显著改善通气。在临床实践中尚未研究反馈的使用。本研究的目的是确定在院外心脏复苏期间使用实时反馈是否可以提高通气率和容量符合预定义目标的依从性。
这是加拿大安大略省的四项护理服务的前后研究。我们招募了成人院外心脏骤停(OHCA)患者,其中使用 ZOLL Accuvent®设备测量通气率和容量。在无反馈的前阶段(无反馈),Accuvent®用于测量通气,但提供者对实时反馈不知情。在后阶段(有反馈),启用了反馈仪表板,提供者使用实时反馈来指导他们的通气。整个研究期间,复苏的所有其他方面都保持一致。研究的主要目的是比较有实时反馈和无实时反馈时符合预定义通气目标的每个病例的比例。我们还检查了高级气道对通气质量的影响,并检查了通气参数与循环恢复之间的关联。
我们在研究中招募了 412 名患者(前阶段无反馈 191 例,后阶段有反馈 221 例)。总体而言,与前阶段(无实时反馈)相比,后阶段(有实时反馈)的通气率和容量均有显著改善。我们没有发现使用或不使用高级气道、或心脏骤停期间或心脏骤停后通气符合率有任何差异。
使用实时反馈与心肺复苏期间符合预定义目标的通气比例增加有关。需要进一步努力提高实时通气反馈的使用,并确定通气对患者结局的影响。