产生γ重链的甲状腺髓外浆细胞瘤

Extramedullary plasmacytoma of the thyroid gland producing gamma heavy chain.

作者信息

Matsubayashi S, Tamai H, Suzuki T, Matsuzuka F, Miyauchi A, Kobayashi N, Fukata S, Kuma K, Yanaihara N, Nagataki S

出版信息

Endocrinol Jpn. 1985 Jun;32(3):427-33. doi: 10.1507/endocrj1954.32.427.

DOI:10.1507/endocrj1954.32.427

Abstract

We encountered a 65-year-old man with gamma heavy chain disease associated with extramedullary plasmacytoma of the thyroid gland. Serum electrophoresis revealed an abnormal fast gamma band that cross-reacted with anti-IgG (Fc gamma) sera immunoelectrophoretically. Intracytoplasmic monoclonal immunoglobulin, IgG (Fc gamma), was demonstrated in thyroid tissue sections using an indirect immunofluorescence method. After surgery, the serum abnormal fast gamma band disappeared. At the time of writing, the patient has survived 18 months post-surgery.

摘要

我们遇到一名65岁男性，患有与甲状腺髓外浆细胞瘤相关的γ重链病。血清电泳显示一条异常的快速γ带，免疫电泳时与抗IgG（Fcγ）血清发生交叉反应。使用间接免疫荧光法在甲状腺组织切片中证实了胞浆内单克隆免疫球蛋白IgG（Fcγ）。手术后，血清异常快速γ带消失。在撰写本文时，该患者术后已存活18个月。