Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, P.R. China.
Sun Yat-sen Global Health Institute, School of Public Health and Institute of State Governance, Sun Yat-sen University, Guangzhou, P.R. China.
J Alzheimers Dis. 2024;101(4):1321-1331. doi: 10.3233/JAD-240583.
Previous estimates on future socioeconomic costs of dementia in China are inconsistent, and the main drivers of these costs are unclear.
This study projected future socioeconomic costs (healthcare, formal social care, and informal care costs) and value of quality adjusted life years (QALYs) lost to dementia in China and assessed drivers of socioeconomic costs.
Based on our prior projection on dementia cases to 2050 by a Markov model, we forecasted future socioeconomic costs and the value of QALYs from a societal perspective, utilizing the China Health and Retirement Longitudinal Study and the Chinese Longitudinal Healthy Longevity Survey. In our main analysis, dementia incidence increased by 2.9% annually, while sensitivity analyses considered a flat or 1.0% annual decrease in the temporal trend of dementia incidence. Furthermore, we decomposed socioeconomic costs changes (2018 US$) into population growth, population aging, dementia prevalence and average socioeconomic costs per case.
The annual socioeconomic costs and value of QALYs lost to dementia will reach $1,233 billion and $702 billion by 2050. If dementia incidence stays constant or decreases by 1.0% annually, the costs and QALYs would respectively decrease by 34% or 43% in 2050. Informal care is currently, and projected to remain, the largest share of socioeconomic costs. Population aging and rising dementia prevalence will mainly drive the growth in socioeconomic costs through 2050.
Dementia casts an increasingly large economic burden on Chinese society, mainly driven by fast aging population and growing dementia prevalence.
此前对中国痴呆症未来社会经济成本的估计不一致,且这些成本的主要驱动因素尚不清楚。
本研究预测了中国痴呆症未来的社会经济成本(医疗保健、正规社会护理和非正规护理成本)和因痴呆症而损失的质量调整生命年(QALYs)的价值,并评估了社会经济成本的驱动因素。
基于我们之前使用马尔可夫模型对 2050 年痴呆病例的预测,我们从社会角度预测了未来的社会经济成本和 QALYs 价值,利用中国健康与退休纵向研究和中国长寿纵向研究的数据。在我们的主要分析中,痴呆症的发病率以每年 2.9%的速度增长,而敏感性分析则考虑了痴呆症发病率随时间的趋势呈持平或每年下降 1.0%的情况。此外,我们将社会经济成本变化(2018 年美元)分解为人口增长、人口老龄化、痴呆症患病率和每个病例的平均社会经济成本。
到 2050 年,每年因痴呆症导致的社会经济成本和损失的 QALYs 将分别达到 1.233 万亿美元和 7020 亿美元。如果痴呆症发病率保持不变或每年下降 1.0%,那么到 2050 年,成本和 QALYs 将分别减少 34%或 43%。非正规护理目前是且预计将继续成为社会经济成本的最大组成部分。人口老龄化和不断上升的痴呆症患病率将是导致 2050 年社会经济成本增长的主要因素。
痴呆症给中国社会带来的经济负担越来越大,主要原因是人口快速老龄化和痴呆症患病率不断上升。