Faculty of Nursing, Chulalongkorn University, Bangkok, Thailand; Nam Dinh University of Nursing, Viet Nam.
Faculty of Nursing, Chulalongkorn University, Bangkok, Thailand; Asian Wisdom Care Research Unit, Chulalongkorn University, Bangkok, Thailand.
Eur J Oncol Nurs. 2024 Oct;72:102691. doi: 10.1016/j.ejon.2024.102691. Epub 2024 Sep 12.
this study aims to develop and test a model examining the causal relationship between self-efficacy, social support, fatigue, pain, functional status, and health-related quality of life (HRQL).
A cross-sectional correlation study was conducted using a multi-stage sampling technique to recruit 256 individuals aged 20 to 59 with colorectal cancer (CRC) post-surgery from three hospitals in Northern Vietnam. The hypothesized model, based on Ferrans' HRQL conceptual model and literature review, was validated using structural equation modeling (SEM) and Mplus.
the model fit the data well, explaining 52% of the variance of HRQL. Self-efficacy emerged as the most influential factor directly impacting HRQL (β = .494, p < .05) and also had negative indirect effects on HRQL through fatigue and pain (β = -.271, p < .05). Social support had a positive direct (β = .406, p < .001) and negative indirect effects on HRQL via fatigue and pain (β = -.143, p < .05). Fatigue and pain had negative indirect effects on HRQL through functional status (β = -.336, p < .05 and β = -.219, p < .05, respectively). Functional status had a positive direct effect on HRQL (β = .418, p < .001).
The study's findings highlight the importance of improving self-efficacy, social support, and functional status, while reducing fatigue and pain to enhance HRQL among individuals with CRCpost-surgery. These insights can inform the development of targeted interventions to improve the well-being of this population.
本研究旨在开发和检验一个模型，该模型检验了自我效能感、社会支持、疲劳、疼痛、功能状态与健康相关生活质量（HRQL）之间的因果关系。
采用多阶段抽样技术，对来自越南北部 3 家医院的 256 名 20 至 59 岁的结直肠癌（CRC）术后患者进行了横断面相关性研究。基于 Ferrans 的 HRQL 概念模型和文献综述，假设模型采用结构方程建模（SEM）和 Mplus 进行验证。
该模型很好地拟合了数据，解释了 HRQL 的 52%的方差。自我效能感是对 HRQL 有直接影响的最主要因素（β=0.494，p<0.05），并且通过疲劳和疼痛对 HRQL 产生负向间接影响（β=-0.271，p<0.05）。社会支持对 HRQL 有正向直接影响（β=0.406，p<0.001），并通过疲劳和疼痛对 HRQL 产生负向间接影响（β=-0.143，p<0.05）。疲劳和疼痛通过功能状态对 HRQL 产生负向间接影响（β=-0.336，p<0.05 和β=-0.219，p<0.05）。功能状态对 HRQL 有正向直接影响（β=0.418，p<0.001）。
研究结果强调了提高自我效能感、社会支持和功能状态，同时减少疲劳和疼痛对提高 CRC 术后个体 HRQL 的重要性。这些发现可以为制定针对该人群的干预措施提供信息，以提高他们的幸福感。
