Department of Neurology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
BMC Neurol. 2024 Sep 20;24(1):355. doi: 10.1186/s12883-024-03866-y.
Several cases of autoimmune disease onset after treatment for Cushing's syndrome have been reported.
Herein, we report a case of myasthenia gravis crisis in a 51-year-old woman 2 months after adrenalectomy for adrenal Cushing's syndrome accompanied by takotsubo cardiomyopathy. The resolution of excessive endogenous cortisol after adrenalectomy may have triggered the onset of previously latent myasthenia gravis.
Observing the similarities in symptoms between myasthenia gravis and adrenal crisis, which can sometimes be challenging to differentiate, is essential. Moreover, the presence of takotsubo cardiomyopathy as a non-motor manifestation of myasthenic crisis must be noted.
皮质醇增多症治疗后出现自身免疫性疾病发病的病例已有报道。
本文报告了一例 51 岁女性患者，在因肾上腺皮质醇增多症接受肾上腺切除术 2 个月后发生肌无力危象合并应激性心肌病。术后内源性皮质醇过量的消除可能引发了先前潜伏的重症肌无力。
观察重症肌无力和肾上腺危象之间有时难以区分的症状相似性至关重要。此外，必须注意到应激性心肌病作为肌无力危象的非运动表现。
