库欣综合征伴 Takotsubo 心肌病的重症肌无力在肾上腺切除术后的发病：一例报告。
Cushing's syndrome developing myasthenia gravis with takotsubo cardiomyopathy after adrenalectomy: a case report.
机构信息
Department of Neurology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.
出版信息
BMC Neurol. 2024 Sep 20;24(1):355. doi: 10.1186/s12883-024-03866-y.
BACKGROUND
Several cases of autoimmune disease onset after treatment for Cushing's syndrome have been reported.
CASE PRESENTATION
Herein, we report a case of myasthenia gravis crisis in a 51-year-old woman 2 months after adrenalectomy for adrenal Cushing's syndrome accompanied by takotsubo cardiomyopathy. The resolution of excessive endogenous cortisol after adrenalectomy may have triggered the onset of previously latent myasthenia gravis.
CONCLUSIONS
Observing the similarities in symptoms between myasthenia gravis and adrenal crisis, which can sometimes be challenging to differentiate, is essential. Moreover, the presence of takotsubo cardiomyopathy as a non-motor manifestation of myasthenic crisis must be noted.
背景
皮质醇增多症治疗后出现自身免疫性疾病发病的病例已有报道。
病例介绍
本文报告了一例 51 岁女性患者，在因肾上腺皮质醇增多症接受肾上腺切除术 2 个月后发生肌无力危象合并应激性心肌病。术后内源性皮质醇过量的消除可能引发了先前潜伏的重症肌无力。
结论
观察重症肌无力和肾上腺危象之间有时难以区分的症状相似性至关重要。此外，必须注意到应激性心肌病作为肌无力危象的非运动表现。
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