Layton Alison, Alexis Andrew, Baldwin Hilary, Beissert Stefan, Bettoli Vincenzo, Del Rosso James, Dréno Brigitte, Gold Linda Stein, Harper Julie, Lynde Charles, Thiboutot Diane, Weiss Jonathan, Tan Jerry
Hull York Medical School, University of York, York, United Kingdom.
Harrogate and District NHS Foundation Trust, Harrogate, United Kingdom.
JAAD Int. 2021 Aug 17;5:41-48. doi: 10.1016/j.jdin.2021.06.006. eCollection 2021 Dec.
The physical sequelae of acne include erythema, hyperpigmentation, and scarring, which are highly burdensome for patients. Early, effective treatment can potentially limit and prevent sequelae development, but there is a need for guidance for and evidence of prevention-oriented management to improve patient outcomes.
To identify unmet needs of acne sequelae and generate expert recommendations to address gaps in clinical guidance.
The Personalizing Acne: Consensus of Experts panel of 13 dermatologists used a modified Delphi approach to achieve a consensus on the clinical aspects of acne sequelae. A consensus was defined as ≥75% of the dermatologists voting "agree" or "strongly agree." All voting was electronic and blinded.
The panel identified gaps in current guidance and made recommendations related to acne sequelae. These included identification and classification of sequelae, pertinent points to consider for patient consultations, and management aimed at reducing the development of sequelae.
The recommendations are based on expert opinion and made in the absence of high-quality evidence.
The identified gaps should help inform future research and guideline development for acne sequelae. The consensus-based recommendations should also support the process of consultations throughout the patient journey, helping to reduce the development and burden of acne sequelae through improved risk factor recognition, early discussion, and appropriate management.
痤疮的身体后遗症包括红斑、色素沉着和瘢痕形成，给患者带来极大负担。早期有效的治疗可能会限制并预防后遗症的发展，但需要有以预防为导向的管理指导及证据来改善患者预后。
确定痤疮后遗症未满足的需求，并生成专家建议以填补临床指导方面的空白。
由13名皮肤科医生组成的“个性化痤疮：专家共识”小组采用改良的德尔菲法，就痤疮后遗症的临床方面达成共识。共识定义为≥75%的皮肤科医生投票“同意”或“强烈同意”。所有投票均为电子投票且匿名。
该小组确定了当前指导中的空白，并提出了与痤疮后遗症相关的建议。这些建议包括后遗症的识别与分类、患者咨询时需考虑的相关要点，以及旨在减少后遗症发生的管理措施。
这些建议基于专家意见，且缺乏高质量证据。
所确定的空白应有助于为未来痤疮后遗症的研究和指南制定提供信息。基于共识的建议还应支持患者就医全程的咨询过程，通过改善危险因素识别、早期讨论和适当管理，帮助减轻痤疮后遗症的发生和负担。
