College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Guangxi Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China.
Food Chem. 2025 Jan 15;463(Pt 2):141345. doi: 10.1016/j.foodchem.2024.141345. Epub 2024 Sep 17.
Colostrum from yaks and buffaloes possesses substantial nutritional value, yet the complete array of metabolites within remains insufficiently elucidated. This study scrutinizes the metabolite profiles of yak, buffalo, and cow colostrum utilizing targeted metabolomics paired with ultra-performance liquid chromatography-tandem triple quadrupole linear ion trap mass spectrometry (UPLC-QTRAP-MS). The analysis detected 362 metabolites across all samples. Furthermore, 63, 77, and 46 differential metabolites were selected between yak and buffalo colostrum, yak and cow colostrum, and buffalo and cow colostrum, respectively. Yak colostrum notably contained higher concentrations of inositol, glycine, and carnitine, whereas buffalo colostrum was distinguished by a substantial presence of primary bile acids, which facilitate fat digestion. These findings offer profound insights into yak and buffalo colostrum, providing critical data to propel advancements in the dairy industry.
牦牛奶和水牛乳初乳具有很高的营养价值，但其中的代谢物种类仍不够清楚。本研究采用靶向代谢组学结合超高效液相色谱-串联三重四极杆线性离子阱质谱联用技术（UPLC-QTRAP-MS），研究了牦牛、水牛和奶牛初乳的代谢物图谱。分析检测到所有样品中存在 362 种代谢物。此外，在牦牛和水牛乳初乳、牦牛和奶牛乳初乳以及水牛和奶牛乳初乳之间分别选择了 63、77 和 46 种差异代谢物。牦牛乳初乳中肌醇、甘氨酸和肉碱的浓度明显较高，而水牛乳初乳中则大量存在有助于脂肪消化的初级胆汁酸。这些发现深入了解了牦牛和水牛乳初乳，为推动乳制品行业的发展提供了重要数据。
