COVID-19大流行期间全球及风险组分层的成年人幸福感与心理健康：国际COH-FIT研究结果
Global and risk-group stratified well-being and mental health during the COVID-19 pandemic in adults: Results from the international COH-FIT Study.
作者信息
Solmi Marco, Thompson Trevor, Estradé Andrés, Agorastos Agorastos, Radua Joaquim, Cortese Samuele, Dragioti Elena, Vancampfort Davy, Thygesen Lau Caspar, Aschauer Harald, Schlögelhofer Monika, Aschauer Elena, Schneeberger Andres, Huber Christian G, Hasler Gregor, Conus Philippe, Cuénod Kim Q Do, von Känel Roland, Arrondo Gonzalo, Fusar-Poli Paolo, Gorwood Philip, Llorca Pierre-Michel, Krebs Marie-Odile, Scanferla Elisabetta, Kishimoto Taishiro, Rabbani Golam, Skonieczna-Żydecka Karolina, Brambilla Paolo, Favaro Angela, Takamiya Akihiro, Zoccante Leonardo, Colizzi Marco, Bourgin Julie, Kamiński Karol, Moghadasin Maryam, Seedat Soraya, Matthews Evan, Wells John, Vassilopoulou Emilia, Gadelha Ary, Su Kuan-Pin, Kwon Jun Soo, Kim Minah, Lee Tae Young, Papsuev Oleg, Manková Denisa, Boscutti Andrea, Gerunda Cristiano, Saccon Diego, Righi Elena, Monaco Francesco, Croatto Giovanni, Cereda Guido, Demurtas Jacopo, Brondino Natascia, Veronese Nicola, Enrico Paolo, Politi Pierluigi, Ciappolino Valentina, Pfennig Andrea, Bechdolf Andreas, Meyer-Lindenberg Andreas, Kahl Kai G, Domschke Katharina, Bauer Michael, Koutsouleris Nikolaos, Winter Sibylle, Borgwardt Stefan, Bitter Istvan, Balazs Judit, Czobor Pál, Unoka Zsolt, Mavridis Dimitris, Tsamakis Konstantinos, Bozikas Vasilios P, Tunvirachaisakul Chavit, Maes Michael, Rungnirundorn Teerayuth, Supasitthumrong Thitiporn, Haque Ariful, Brunoni Andre R, Costardi Carlos Gustavo, Schuch Felipe Barreto, Polanczyk Guilherme, Luiz Jhoanne Merlyn, Fonseca Lais, Aparicio Luana V, Valvassori Samira S, Nordentoft Merete, Vendsborg Per, Hoffmann Sofie Have, Sehli Jihed, Sartorius Norman, Heuss Sabina, Guinart Daniel, Hamilton Jane, Kane John, Rubio Jose, Sand Michael, Koyanagi Ai, Solanes Aleix, Andreu-Bernabeu Alvaro, Cáceres Antonia San José, Arango Celso, Díaz-Caneja Covadonga M, Hidalgo-Mazzei Diego, Vieta Eduard, Gonzalez-Peñas Javier, Fortea Lydia, Parellada Mara, Fullana Miquel A, Verdolini Norma, Andrlíková Eva, Janků Karolina, Millan Mark J, Honciuc Mihaela, Moniuszko-Malinowska Anna, Łoniewski Igor, Samochowiec Jerzy, Kiszkiel Łukasz, Marlicz Maria, Sowa Paweł, Marlicz Wojciech, Spies Georgina, Stubbs Brendon, Firth Joseph, Sullivan Sarah, Darcin Asli Enez, Aksu Hatice, Dilbaz Nesrin, Noyan Onur, Kitazawa Momoko, Kurokawa Shunya, Tazawa Yuki, Anselmi Alejandro, Cracco Cecilia, Machado Ana Inés, Estrade Natalia, De Leo Diego, Curtis Jackie, Berk Michael, Carvalho Andre F, Ward Philip, Teasdale Scott, Rosenbaum Simon, Marx Wolfgang, Horodnic Adrian Vasile, Oprea Liviu, Alexinschi Ovidiu, Ifteni Petru, Turliuc Serban, Ciuhodaru Tudor, Bolos Alexandra, Matei Valentin, Nieman Dorien H, Sommer Iris, van Os Jim, van Amelsvoort Therese, Sun Ching-Fang, Guu Ta-Wei, Jiao Can, Zhang Jieting, Fan Jialin, Zou Liye, Yu Xin, Chi Xinli, de Timary Philippe, van Winkel Ruud, Ng Bernardo, Peña de León Edilberto, Arellano Ramon, Roman Raquel, Sanchez Thelma, Movina Larisa, Morgado Pedro, Brissos Sofia, Aizberg Oleg, Mosina Anna, Krinitski Damir, Mugisha James, Sadeghi-Bahmani Dena, Sheybani Farshad, Sadeghi Masoud, Hadi Samira, Brand Serge, Errazuriz Antonia, Crossley Nicolas, Ristic Dragana Ignjatovic, López-Jaramillo Carlos, Efthymiou Dimitris, Kuttichira Praveenlal, Kallivayalil Roy Abraham, Javed Afzal, Afridi Muhammad Iqbal, James Bawo, Seb-Akahomen Omonefe Joy, Fiedorowicz Jess, Daskalakis Jeff, Yatham Lakshmi N, Yang Lin, Okasha Tarek, Dahdouh Aïcha, Tiihonen Jari, Shin Jae Il, Lee Jinhee, Mhalla Ahmed, Gaha Lotfi, Brahim Takoua, Altynbekov Kuanysh, Negay Nikolay, Nurmagambetova Saltanat, Jamei Yasser Abu, Weiser Mark, Correll Christoph U
机构信息
University of Ottawa, Department of Psychiatry, Ontario, Canada; The Ottawa Hospital, Department of Mental Health, Ontario, Canada; Ottawa Hospital Research Institute (OHRI) Neurosciences Program, Ottawa Ontario; Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK; Centre for Innovation in Mental Health-Developmental Lab, School of Psychology, University of Southampton, and NHS Trust, Southampton, United Kingdom; Charité Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany.
Centre for Chronic Illness and Ageing, University of Greenwich, London, UK.
出版信息
Psychiatry Res. 2024 Dec;342:115972. doi: 10.1016/j.psychres.2024.115972. Epub 2024 May 23.
International studies measuring wellbeing/multidimensional mental health before/ during the COVID-19 pandemic, including representative samples for >2 years, identifying risk groups and coping strategies are lacking. COH-FIT is an online, international, anonymous survey measuring changes in well-being (WHO-5) and a composite psychopathology P-score, and their associations with COVID-19 deaths/restrictions, 12 a-priori defined risk individual/cumulative factors, and coping strategies during COVID-19 pandemic (26/04/2020-26/06/2022) in 30 languages (representative, weighted non-representative, adults). T-test, χ, penalized cubic splines, linear regression, correlation analyses were conducted. Analyzing 121,066/142,364 initiated surveys, WHO-5/P-score worsened intra-pandemic by 11.1±21.1/13.2±17.9 points (effect size d=0.50/0.60) (comparable results in representative/weighted non-probability samples). Persons with WHO-5 scores indicative of depression screening (<50, 13% to 32%) and major depression (<29, 3% to 12%) significantly increased. WHO-5 worsened from those with mental disorders, female sex, COVID-19-related loss, low-income country location, physical disorders, healthcare worker occupations, large city location, COVID-19 infection, unemployment, first-generation immigration, to age=18-29 with a cumulative effect. Similar findings emerged for P-score. Changes were significantly but minimally related to COVID-19 deaths, returning to near-pre-pandemic values after >2 years. The most subjectively effective coping strategies were exercise and walking, internet use, social contacts. Identified risk groups, coping strategies and outcome trajectories can inform global public health strategies.
在新冠疫情之前/期间衡量幸福感/多维心理健康状况的国际研究尚显不足，这些研究应涵盖超过两年的代表性样本，识别风险群体并确定应对策略。COH-FIT是一项在线国际匿名调查，旨在测量幸福感变化（世界卫生组织-5幸福指数）和综合精神病理学P分数，以及它们与新冠死亡/限制措施、12个先验定义的风险个体/累积因素以及新冠疫情期间（2020年4月26日至2022年6月26日）应对策略之间的关联，调查以30种语言进行（针对有代表性的、加权非代表性的成年人）。研究进行了t检验、χ检验、惩罚三次样条分析、线性回归和相关分析。在分析的121,066/142,364份初始调查中，疫情期间世界卫生组织-5幸福指数/ P分数恶化了11.1±21.1/13.2±17.9分（效应大小d = 0.50/0.60）（在代表性/加权非概率样本中结果相似）。世界卫生组织-5幸福指数得分表明有抑郁筛查迹象（<50，从13%增至32%）和重度抑郁（<29，从3%增至12%）的人群显著增加。世界卫生组织-5幸福指数在患有精神障碍、女性、与新冠相关的损失、低收入国家、身体疾病、医护人员职业、大城市、新冠感染、失业、第一代移民以及18至29岁人群中恶化，且存在累积效应。P分数也有类似发现。这些变化与新冠死亡显著但微弱相关，在两年多后恢复到接近疫情前的水平。最具主观效果的应对策略是锻炼和散步、使用互联网、社交。识别出的风险群体、应对策略和结果轨迹可为全球公共卫生策略提供参考。
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