Agorastos Agorastos, Christogiannis Christos, Mavridis Dimitris, Seitidis Georgios, Kontouli Katerina M, Tsokani Sofia, Koutsiouroumpa Ourania, Tsamakis Kostantinos, Solmi Marco, Thompson Trevor, Correll Christoph U, Dragioti Elena, Bozikas Vasilios P
Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.
University of Ioannina, Department of Primary Education, Ioannina, Greece; Developmental EPI (Evidence synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
Psychiatry Res. 2025 Jun;348:116479. doi: 10.1016/j.psychres.2025.116479. Epub 2025 Mar 31.
Greece faced particular COVID-19-pandemic-related challenges, due to specific socio-cultural-economic/public-health factors and drastic restrictive policies.
To understand trajectories of overall mental and physical health, well-being, emotional states and individual psychopathology in response to pandemic-related restrictive measures within general adult Greek population across the first two pandemic waves.
Using multiple time-point cross-sectional data from the "Collaborative Outcomes study on Health and Functioning during Infection Times" (COH-FIT), we examined changes in outcomes from retrospective pre-pandemic ratings (T0) to three distinct intra-pandemic time points (lockdown 1: T1, between lockdowns: T2, lockdown 2: T3). Primary outcomes included WHO-5 well-being scores and a composite overall psychopathology "P-score", followed by a wide range of secondary outcomes.
10,377 participant responses were evaluated, including 2737 representative-matched participants. Statistically significant differences in well-being and overall psychopathology before and after quarantine (T0 vs. T1-T3), as well as across the assessed time frames (T1, T2, and T3) emerged in both samples. Global mental and physical health, individual psychopathology scores (anxiety, depression, PTSD, OCD, panic, mania, mood swings, sleep and concentration problems), emotional states (anger, helplessness, fear of infection, boredom, frustration, loneliness and overall stress scores), BMI and pain scores also showed statistically significant time differences in both samples, with the exemption of self-injury and suicidal attempt scores, showing lower intra-pandemic scores.
This is the largest multi-wave report on well-being, mental and physical health across different pandemic restriction periods in Greece, suggesting a substantial negative effect of lockdowns on most outcomes at least during the acute pandemic waves.
由于特定的社会文化经济/公共卫生因素以及严厉的限制政策,希腊面临与新冠疫情相关的特殊挑战。
了解在希腊普通成年人群中,在疫情的前两波期间,总体身心健康、幸福感、情绪状态和个体精神病理学对与疫情相关的限制措施的反应轨迹。
利用“感染时期健康与功能协作结果研究”(COH-FIT)的多个时间点横断面数据,我们研究了从疫情前回顾性评分(T0)到三个不同的疫情期间时间点(封锁1:T1,两次封锁之间:T2,封锁2:T3)结果的变化。主要结果包括世界卫生组织-5幸福感得分和综合总体精神病理学“P得分”,随后是广泛的次要结果。
评估了10377名参与者的回复,包括2737名代表性匹配参与者。在两个样本中,隔离前后(T0与T1-T3)以及在评估的时间框架(T1、T2和T3)内,幸福感和总体精神病理学存在统计学上的显著差异。全球身心健康、个体精神病理学得分(焦虑、抑郁、创伤后应激障碍、强迫症、恐慌、躁狂、情绪波动、睡眠和注意力问题)、情绪状态(愤怒、无助、对感染的恐惧、无聊、沮丧、孤独和总体压力得分)、体重指数和疼痛得分在两个样本中也显示出统计学上的显著时间差异,但自我伤害和自杀未遂得分除外,其在疫情期间得分较低。
这是关于希腊不同疫情限制时期幸福感、身心健康的最大规模多波报告,表明封锁至少在疫情急性发作期间对大多数结果有重大负面影响。