Arango Natalia, Rojas-Lechuga María Jesús, Chen Jiwei, Larrosa Francisco, Alegre Berta, Vilaseca Isabel
Servicio de Otorrinolaringología, Hospital Clínic de Barcelona, Barcelona, Spain.
Servicio de Otorrinolaringología, Hospital Clínic de Barcelona, Barcelona, Spain.
Acta Otorrinolaringol Esp (Engl Ed). 2025 Jan-Feb;76(1):31-36. doi: 10.1016/j.otoeng.2024.07.004. Epub 2024 Sep 19.
During the SARS-CoV-2 pandemic, immune-mediated neurological events have been described in patients vaccinated against the virus or who have overcome the disease. Among these events is Idiopathic peripheral facial palsy or Bell's palsy.
To study the incidence of Bell's Palsy in the ENT emergency department of a tertiary hospital in Catalonia during the SARS-CoV-2 pandemic.
Retrospective historical cohort comparison study of patients diagnosed with Bell's palsy between January 2018 and December 2021. Crude incidence rates were calculated as the total number of events divided by person time at risk per 100.000 person-years. Observed (2020, 2021) and historical (2018, 2019) rates were compared using standardized incidence rates with corresponding 95% confidence intervals.
Of the total number of ENT emergency department visits from 2018 to 2021 (22.658), there were 247 cases of Bell's palsy. The incidence rate of Bell's palsy in the pre-pandemic group was 12,2 and 10,9 per 100.000 person-years for 2018 and 2019, respectively. The 2020 standardized incidence rate of Bell's palsy was 0,70 [95% CI 0,49-1,01] and 1,25 [95% CI 0,93-1,67] for 2021. No significant differences were evident between the two groups.
In our cohort, no association was found between vaccination or COVID-19 infection and the development of Bell's Palsy.
在严重急性呼吸综合征冠状病毒2（SARS-CoV-2）大流行期间，已在接种该病毒疫苗或已康复的患者中发现免疫介导的神经系统事件。这些事件包括特发性周围性面神经麻痹或贝尔麻痹。
研究SARS-CoV-2大流行期间加泰罗尼亚一家三级医院耳鼻喉科急诊科贝尔麻痹的发病率。
对2018年1月至2021年12月期间诊断为贝尔麻痹的患者进行回顾性历史队列比较研究。粗发病率计算为事件总数除以每100000人年的风险人时。使用标准化发病率及其相应的95%置信区间比较观察到的（2020年、2021年）和历史（2018年、2019年）发病率。
在2018年至2021年耳鼻喉科急诊科的总就诊人数（22658人）中，有247例贝尔麻痹病例。2018年和2019年大流行前组贝尔麻痹的发病率分别为每100000人年12.2例和10.9例。2020年贝尔麻痹的标准化发病率为0.70[95%置信区间0.49 - 1.01]，2021年为1.25[95%置信区间0.93 - 1.67]。两组之间无明显差异。
在我们的队列中，未发现疫苗接种或新冠病毒感染与贝尔麻痹的发生之间存在关联。
