Hu Wen-Xiao, Xiao Su-Ping, Chen Min, Qian Dan
Experimental Research Center, China Academy of Chinese Medical Sciences Beijing 100700, China.
China National Traditional Chinese Medicine Co., Ltd. Beijing 100195, China.
Zhongguo Zhong Yao Za Zhi. 2024 Sep;49(17):4545-4552. doi: 10.19540/j.cnki.cjcmm.20240518.101.
Medicine and food homology culture has a long history in China. With the continuous improvement of people's living standards, there has been a growing investment in health care, leading to significant development in the health industry. Medicinal and food homologous substances, receiving increasing attention, have become the breakthrough and mainstay of the health industry, with broad prospects for related industries. However, the medicinal and edible industry currently faces numerous challenges, especially regarding the research on quality standards for medicinal and food homologous substances, where the study of food attributes is still in its infancy. Therefore, this article elaborated on the current research status of quality standards for medicinal and food homologous substances, clarified the confusion surrounding the concept of medicinal and food homologous substances, and analyzed the weaknesses in the research on food attributes in the quality standards of medicinal and food homologous substances, as well as the lack of unified safety indicators. Based on the dual attributes of medicinal and food homologous substances, it is suggested that research on quality stan-dards should encompass authenticity, safety, nutrition, and efficacy. Under the premise of ensuring authenticity, the safety of exogenous toxic substances should be evaluated in combination with their dual attributes. In the formulation of standards, the nutritional aspect of food properties should be strengthened, and different indicators should be selected for comprehensive quality control based on the sources and properties of medicinal and food homologous substances. By employing multiple techniques for holistic control from various perspectives, a set of systematic quality standards applicable to medicinal and food homologous substances can be established. This study is expected to provide references for the quality control, safe use, and regulation of medicinal and food homologous substances, thereby promoting the healthy development of the entire industry.
药食同源文化在中国有着悠久的历史。随着人们生活水平的不断提高，对保健的投入日益增加，推动了健康产业的显著发展。受到越来越多关注的药食同源物质，已成为健康产业的突破口和支柱，相关产业前景广阔。然而，目前药食同源产业面临诸多挑战，尤其是药食同源物质质量标准的研究，其中食品属性的研究仍处于起步阶段。因此，本文阐述了药食同源物质质量标准的研究现状，厘清了药食同源物质概念的混淆之处，分析了药食同源物质质量标准中食品属性研究的薄弱环节以及缺乏统一安全指标的问题。基于药食同源物质的双重属性，建议质量标准研究应涵盖真伪性、安全性、营养性和功效性。在确保真伪性的前提下，应结合其双重属性对外源有毒物质的安全性进行评价。在标准制定中，应强化食品属性的营养方面，根据药食同源物质的来源和性质选择不同指标进行综合质量控制。通过从多个角度采用多种技术进行整体控制，可建立一套适用于药食同源物质的系统质量标准。本研究有望为药食同源物质的质量控制、安全使用和监管提供参考，从而推动整个产业的健康发展。
