Shimizu T, Sengoku K
Jpn J Antibiot. 1985 May;38(5):1198-202.
Cefminox (CMNX, MT-141), a new cephamycin, was studied of its transfer into the serum and tissues with following results: After an intravenous injection of 1 g of CMNX, the serum concentration of the drug achieved in the uterine artery was almost equal to that in the elbow vein, showing good transfer of the drug. After an intravenous injection of 1 g of CMNX, favorable results were also obtained for concentrations achieved in all of the adnexal and uterine tissues studied. From the results obtained, it is expected that CMNX is highly effective in particular for infections caused by E. coli, Klebsiella sp. and B. fragilis.
头孢米诺（CMNX，MT - 141）是一种新型头孢霉素，对其向血清和组织中的转移情况进行了研究，结果如下：静脉注射1g头孢米诺后，子宫动脉中的药物血清浓度几乎与肘静脉中的相等，表明该药物具有良好的转移特性。静脉注射1g头孢米诺后，在所研究的所有附件和子宫组织中所达到的浓度也取得了良好结果。从所获结果来看，预计头孢米诺对由大肠杆菌、克雷伯菌属和脆弱拟杆菌引起的感染特别有效。
