Costello Anna, Rasooly Irit, Weiss Pamela
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia.
Arthritis Care Res (Hoboken). 2025 Mar;77(3):283-290. doi: 10.1002/acr.25438. Epub 2024 Oct 15.
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood and a disease for which we have safe and effective therapies. Early diagnosis of JIA enables timely initiation of therapy and improves long-term disease outcomes. However, many patients with JIA experience prolonged diagnostic delays and have a turbulent course to diagnosis. In this narrative review, we explore the importance of early diagnosis in JIA, what is known about time to diagnosis and diagnostic trajectory, and factors that contribute to delayed diagnosis. We also discuss next steps to improve time to diagnosis for these vulnerable patients.
幼年特发性关节炎(JIA)是儿童期最常见的风湿性疾病,且我们有针对该疾病的安全有效的治疗方法。JIA的早期诊断能够及时开始治疗并改善疾病的长期预后。然而,许多JIA患者经历了长时间的诊断延迟,诊断过程波折。在这篇叙述性综述中,我们探讨了JIA早期诊断的重要性、关于诊断时间和诊断轨迹的已知情况,以及导致诊断延迟的因素。我们还讨论了针对这些易受影响的患者缩短诊断时间的后续措施。