Jiang Feng, Liu Xiao-Tian, Hu Ze, Liao Wei, Li Shuo-Yi, Zhu Rui-Fang, Mao Zhen-Xing, Hou Jian, Akhtar Sohail, Ahmad Fayaz, Mehmood Tahir, Wang Chong-Jian
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Department of Mathematics and Statistics, The University of Haripur, Haripur, Pakistan.
J Geriatr Cardiol. 2024 Aug 28;21(8):799-806. doi: 10.26599/1671-5411.2024.08.006.
Limited research has explored the impact of cardiovascular disease (CVD) on healthy life expectancy (HLE) especially in resource-limited areas. This study aimed to investigate the association between CVD and HLE in Chinese rural population.
This study included 11,994 participants aged 45 years and older from the baseline and follow-up surveys of the Henan rural cohort study. Healthy status was measured via a Visual Analogue Scale. The multistate Markov model was applied to estimate the association between CVD and transitions in health, unhealthiness and death. Gender-specific total life expectancy, HLE and unhealthy life expectancy were calculated by the multistate life table method.
During a mean follow-up time of 3.85 (3.84-3.86) years, there were 588 deaths recorded. For individuals with CVD, the risk of switching from health to unhealthiness status was increased by 71% [hazard ratio (HR) = 1.71, 95% CI: 1.42-2.07], the chance of recovery was reduced by 30% (HR = 0.70, 95% CI: 0.60-0.82). Men aged 45 years without CVD could gain an extra 7.08 (4.15-10.01) years of HLE and lose 4.00 (1.60-6.40) years of unhealthy life expectancy compared to their peers with CVD, respectively. The corresponding estimates among women were 8.62 (5.55-11.68) years and 5.82 (2.59-9.04) years, respectively.
This study indicated that CVD was significantly associated with poorer health status and lower HLE among Chinese rural population. It is an important public health policy to adopt targeted measures to reduce the CVD burden and enhance the quality of life and HLE in resource-limited areas.
有限的研究探讨了心血管疾病（CVD）对健康预期寿命（HLE）的影响，尤其是在资源有限的地区。本研究旨在调查中国农村人口中CVD与HLE之间的关联。
本研究纳入了来自河南农村队列研究基线和随访调查的11994名45岁及以上的参与者。通过视觉模拟量表测量健康状况。应用多状态马尔可夫模型来估计CVD与健康、不健康和死亡转变之间的关联。通过多状态生命表法计算特定性别的总预期寿命、HLE和不健康预期寿命。
在平均3.85（3.84 - 3.86）年的随访期内，记录到588例死亡。对于患有CVD的个体，从健康状态转变为不健康状态的风险增加了71%[风险比（HR）= 1.71，95%置信区间（CI）：1.42 - 2.07]，康复的机会减少了30%（HR = 0.70，95% CI：0.60 - 0.82）。与患有CVD的同龄人相比，45岁无CVD的男性分别可多获得7.08（4.15 - 10.01）年的HLE，并减少4.00（1.60 - 6.40）年的不健康预期寿命。女性的相应估计值分别为8.62（5.55 - 11.68）年和5.82（2.59 - 9.04）年。
本研究表明，CVD与中国农村人口中较差的健康状况和较低的HLE显著相关。采取针对性措施减轻CVD负担并提高资源有限地区的生活质量和HLE是一项重要的公共卫生政策。
