中国农村地区老年高血压患者的患病率及健康调整生命预期。
Prevalence and Health-Adjusted Life Expectancy Among Older Adults With Hypertension in Chinese Rural Areas.
机构信息
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Department of Applied Statistics, School of Statistics and Big Data, Henan University of Economics and Law, Zhengzhou, China.
出版信息
Front Public Health. 2022 Mar 1;10:802195. doi: 10.3389/fpubh.2022.802195. eCollection 2022.
BACKGROUND
The objectives of the present study were to explore the epidemiological characteristics of hypertension among rural older adults in resource-limited regions, and then evaluate the loss of health-adjusted life expectancy due to hypertension.
METHODS
Participants aged between 60 and 79 years were enrolled from Henan rural cohort study. The prevalence, awareness, treatment, and control of hypertension were detailed across subgroups. Variances within subgroups were identified Student's t tests or one-way ANOVA for continuous variables and chi-squared tests for categorical ones, and logistic regression model was employed to detect the potential influencing factors. The health-adjusted life expectancy was calculated by the Sullivan method with EuroqOL-5D data.
RESULTS
Among 16,785 participants, 7,472 (44.52%) were attacked by hypertension, 4,858 (65.02%) had been already aware of their condition, 4,009 (53.65%) were taking antihypertensive medication for treatment, while only 1,478 (19.78%) had their hypertension controlled. The prevalence of hypertension was significantly higher among women than men and it increased with age for both genders. For the older ones aged 60 years, the life expectancy was 22.0872 years and the health-adjusted life expectancy was 15.5578 and 15.9418 for those with or without hypertension, respectively. Namely, in this particular age group, subjects without hypertension could gain 0.3840 years of health-adjusted life expectancy.
CONCLUSION
The prevalence of hypertension was relatively high while the awareness, treatment, and control were fairly low. The health-adjusted life expectancy of older adults in resource-limited areas could increase from the reduction of hypertension. There is an urgent need for strategies pertaining to the prevention and treatment of hypertension.
CLINICAL TRIAL REGISTRATION
The Henan Rural Cohort Study has been registered at the Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). Date of registration: 06 July, 2015. http://www.chictr.org.cn/showproj.aspx?proj=11375.
背景
本研究旨在探讨资源有限地区农村老年人群高血压的流行病学特征，然后评估高血压导致的健康调整期望寿命损失。
方法
参与者年龄在 60 至 79 岁之间，来自河南农村队列研究。详细描述了各亚组的高血压患病率、知晓率、治疗率和控制率。采用方差分析（连续变量）和卡方检验（分类变量）分析组内差异，采用 logistic 回归模型检测潜在的影响因素。使用 Sullivan 方法和 Euroqol-5D 数据计算健康调整期望寿命。
结果
在 16785 名参与者中，7472 名（44.52%）患有高血压，4858 名（65.02%）已经知晓自己的病情，4009 名（53.65%）正在服用降压药物进行治疗，而只有 1478 名（19.78%）的高血压得到了控制。女性高血压患病率明显高于男性，且男女患病率均随年龄增长而升高。对于 60 岁的老年人，期望寿命为 22.0872 年，有或无高血压的健康期望寿命分别为 15.5578 年和 15.9418 年。即在这个特定年龄组中，没有高血压的受试者的健康调整期望寿命可以增加 0.3840 年。
结论
高血压的患病率相对较高，而知晓率、治疗率和控制率较低。资源有限地区老年人群的健康调整期望寿命可以通过降低高血压来提高。迫切需要制定针对高血压预防和治疗的策略。
临床试验注册
河南农村队列研究已在中国临床试验注册中心（注册号：ChiCTR-OOC-15006699）注册。注册日期：2015 年 7 月 6 日。http://www.chictr.org.cn/showproj.aspx?proj=11375。
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