Research Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, P.O. Box: 19395-4763, Tehran, Islamic Republic of Iran.
Students' Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran.
Health Qual Life Outcomes. 2021 Sep 26;19(1):225. doi: 10.1186/s12955-021-01861-2.
Cardiovascular diseases (CVDs) are among the most common causes of death worldwide, including in Iran. Considering the adverse effects of CVDs on physical and psychosocial health; this study aims to investigate the association between experience of CVDs and health-related quality of life (HRQoL) in adult participants of the Tehran Lipid and Glucose Study (TLGS).
The participants of this cross-sectional study were 7009 adults (≥ 20 years) who participated in the TLGS during 2014-2017. Demographic information and HRQoL data was collected through validated questionnaires by trained interviewers. HRQoL was assessed by the Iranian version of the SF-12 questionnaire. Data was analyzed using the SPSS software.
The mean age of participants was 46.8 ± 14.6 years and 46.1% of them were men. A total of 9.0% of men and 4.4% of women had CVDs. In men, the mean physical HRQoL summary score was significantly lower in those with CVDs compared to those without CVDs (46.6 ± 0.8 vs. 48.5 ± 0.7, p > 0.001). In women, the mean mental HRQoL summary scores was significantly lower in those with CVDs compared to those without CVDs (42.8 ± 1.0 vs. 45.2 ± 0.5, p = 0.009). In adjusted models, men with CVDs were more likely to report poor physical HRQoL compared to men without CVDs (OR(95%CI): 1.93(1.32-2.84), p = 0.001); whereas for women, the chance of reporting poor mental HRQoL was 68% higher in those with CVDs than those without CVDs (OR(95%CI): 1.68(1.11-2.54), p = 0.015).
The findings of the current study indicate poorer HRQoL in those who experienced CVDs compared to their healthy counterparts with a sex specific pattern. While for men, CVDs were associated with more significant impairment in the physical dimension of HRQoL, women experienced a similar impairment in the mental dimension of HRQoL.
心血管疾病（CVDs）是全球范围内最常见的死亡原因之一，包括在伊朗。考虑到 CVDs 对身体和心理健康的不良影响；本研究旨在探讨伊朗德黑兰血脂和血糖研究（TLGS）中成年参与者 CVDs 经历与健康相关生活质量（HRQoL）之间的关系。
本横断面研究的参与者为 7009 名成年人（≥ 20 岁），他们于 2014-2017 年参加了 TLGS。通过经过验证的调查问卷，由经过培训的访谈员收集人口统计学信息和 HRQoL 数据。HRQoL 通过伊朗版 SF-12 问卷进行评估。使用 SPSS 软件进行数据分析。
参与者的平均年龄为 46.8±14.6 岁，其中 46.1%为男性。共有 9.0%的男性和 4.4%的女性患有 CVDs。在男性中，与无 CVDs 的人相比，患有 CVDs 的人身体 HRQoL 综合评分明显较低（46.6±0.8 与 48.5±0.7，p>0.001）。在女性中，与无 CVDs 的人相比，患有 CVDs 的人心理 HRQoL 综合评分明显较低（42.8±1.0 与 45.2±0.5，p=0.009）。在调整模型中，与无 CVDs 的男性相比，患有 CVDs 的男性更有可能报告身体 HRQoL 较差（OR（95%CI）：1.93（1.32-2.84），p=0.001）；而对于女性，与无 CVDs 的女性相比，患有 CVDs 的女性报告心理 HRQoL 较差的几率高 68%（OR（95%CI）：1.68（1.11-2.54），p=0.015）。
本研究结果表明，与健康对照组相比，患有 CVDs 的人的 HRQoL 较差，具有性别特异性模式。虽然对于男性来说，CVDs 与身体 HRQoL 维度的更显著损伤有关，但女性在心理 HRQoL 维度也经历了类似的损伤。
