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男性乳腺浸润性小叶癌:一例报告。

Invasive lobular carcinoma of the male breast: A case report.

作者信息

Zebbakh Hajar, Sassi Samia, Adjou Nada, Omor Youssef, Latib Rachida, Lamalmi Najat, Amalik Sanae

机构信息

Department of Radiology, National Institute of Oncology, Rabat, Morocco.

Department of Pathology, Ibn Sina Teaching Hospital, Mohammed V University, Rabat, Morocco.

出版信息

Radiol Case Rep. 2024 Sep 12;19(12):5758-5761. doi: 10.1016/j.radcr.2024.08.063. eCollection 2024 Dec.

DOI:10.1016/j.radcr.2024.08.063
PMID:39308622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11416471/
Abstract

Invasive lobular carcinoma (ILC) is a rare type of male breast cancer, representing about 1% of cases. It often presents with a palpable mass and sometimes nipple changes, but is usually diagnosed late. ILC is more likely to be estrogen and progesterone receptor-positive and usually HER-2 negative. Its diffuse growth pattern makes it difficult to detect with imaging. Treatment typically follows protocols for female breast cancer, including surgery, chemotherapy, and hormone therapy, with tamoxifen being commonly used. Further research is needed to better understand its pathogenesis and to develop more effective, tailored treatments.

摘要

浸润性小叶癌(ILC)是男性乳腺癌的一种罕见类型,约占病例的1%。它通常表现为可触及的肿块,有时伴有乳头改变,但通常诊断较晚。ILC更可能为雌激素和孕激素受体阳性,通常HER-2阴性。其弥漫性生长模式使得通过影像学检查难以发现。治疗通常遵循女性乳腺癌的方案,包括手术、化疗和激素治疗,他莫昔芬是常用药物。需要进一步研究以更好地了解其发病机制并开发更有效、更具针对性的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9f9/11416471/f40e741b17a9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9f9/11416471/d393504defcd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9f9/11416471/f40e741b17a9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9f9/11416471/d393504defcd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9f9/11416471/f40e741b17a9/gr3.jpg

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本文引用的文献

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Differences between invasive lobular and invasive ductal carcinoma of the breast: results and therapeutic implications.乳腺浸润性小叶癌与浸润性导管癌的差异:结果及治疗意义
Ther Adv Med Oncol. 2016 Jul;8(4):261-6. doi: 10.1177/1758834016644156. Epub 2016 Apr 25.
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Invasive lobular carcinoma of the male breast: A rare histology of an uncommon disease.男性乳腺浸润性小叶癌:一种罕见疾病的罕见组织学类型。
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小叶性乳腺癌:发病率及遗传和非遗传风险因素
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Am J Hum Genet. 1998 Mar;62(3):676-89. doi: 10.1086/301749.
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