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移行细胞癌的罕见表现：手部受累的病例报告

Uncommon presentation of transitional cell carcinoma: A case report of hand involvement.

作者信息

Sanei-Far Zahra, Gharib Masoumeh

机构信息

Student Research Committee Mashhad University of Medical Sciences Mashhad Iran.

Department of Pathology, Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.

出版信息

Clin Case Rep. 2024 Sep 20;12(9):e9358. doi: 10.1002/ccr3.9358. eCollection 2024 Sep.

DOI:10.1002/ccr3.9358
PMID:39308663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11413630/
Abstract

It is uncommon to see bladder cancer metastases in the hand. A 65-year-old man had bladder cancer surgery 3 years ago. His axilla and wrist swelled after surgery. Final amputation was necessary as the cancer had spread to hand. Transitional cell carcinoma was detected by immunohistochemistry with GATA-3, CK7, CK20, and p63 positivity.

摘要

膀胱癌转移至手部的情况并不常见。一名65岁男性3年前接受了膀胱癌手术。术后其腋窝和手腕出现肿胀。由于癌症已扩散至手部，最终不得不进行截肢。通过免疫组织化学检测发现为移行细胞癌，GATA-3、CK7、CK20和p63呈阳性。

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本文引用的文献

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Circulating tumour cells for early detection of clinically relevant cancer.循环肿瘤细胞用于早期检测临床相关癌症。
Nat Rev Clin Oncol. 2023 Jul;20(7):487-500. doi: 10.1038/s41571-023-00781-y. Epub 2023 Jun 2.
2
Cancer Metastases to the Hand: A Systematic Review and Meta-analysis.癌症转移至手部：系统评价和荟萃分析。
Hand (N Y). 2024 Sep;19(6):865-874. doi: 10.1177/15589447231153175. Epub 2023 Mar 1.
3
Molecular Markers in Urinary Bladder Cancer: Applications for Diagnosis, Prognosis and Therapy.膀胱癌中的分子标志物：在诊断、预后和治疗中的应用
Vet Sci. 2022 Feb 28;9(3):107. doi: 10.3390/vetsci9030107.
4
Direct Smear Versus Liquid-Based Cytology in the Diagnosis of Bladder Lesions.直接涂片与液基细胞学检查在膀胱病变诊断中的应用比较
Iran J Pathol. 2022 Winter;17(1):56-64. doi: 10.30699/IJP.2021.528171.2646. Epub 2021 Nov 15.
5
MicroRNA engineered umbilical cord stem cell-derived exosomes direct tendon regeneration by mTOR signaling.微小 RNA 工程化脐带干细胞来源的外泌体通过 mTOR 信号通路指导肌腱再生。
J Nanobiotechnology. 2021 Jun 5;19(1):169. doi: 10.1186/s12951-021-00906-4.
6
Management of transitional cell carcinoma of the urinary bladder in dogs: a review.犬膀胱移行细胞癌的管理：综述
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7
Differential expression of GATA-3 in urothelial carcinoma variants.GATA-3 在尿路上皮癌变异型中的差异表达。
Hum Pathol. 2014 Jul;45(7):1466-72. doi: 10.1016/j.humpath.2014.02.023. Epub 2014 Mar 15.
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GATA-3 immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder.GATA-3 免疫组化在膀胱腺癌鉴别诊断中的应用。
Am J Surg Pathol. 2013 Nov;37(11):1756-60. doi: 10.1097/PAS.0b013e31829cdba7.
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[A case of bladder cancer with metastasis to the bone of the hand].[一例膀胱癌转移至手部骨骼的病例]
Hinyokika Kiyo. 2013 Feb;59(2):129-31.
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Cancer Prev Res (Phila). 2013 May;6(5):466-76. doi: 10.1158/1940-6207.CAPR-12-0358. Epub 2013 Mar 26.