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一篇叙述性综述:养殖肌肉肉类和海产品的3D生物打印及其在食品工业中的潜力。

A narrative review: 3D bioprinting of cultured muscle meat and seafood products and its potential for the food industry.

作者信息

Gurel Mediha, Rathod Nikheel, Cabrera Laura Y, Voyton Stephen, Yeo Miji, Ozogul Fatih, Ozbolat Ibrahim T

机构信息

Biotechnology Research and Application Center, Cukurova University, 01330, Adana, Turkey.

Electronic and Automation Department, Bitlis Eren University, Bitlis, 13000, Turkey.

出版信息

Trends Food Sci Technol. 2024 Oct;152. doi: 10.1016/j.tifs.2024.104670. Epub 2024 Aug 14.

DOI:10.1016/j.tifs.2024.104670
PMID:39309029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11412102/
Abstract

The demand for meat and seafood products has been globally increasing for decades. To address the environmental, social, and economic impacts of this trend, there has been a surge in the development of three-dimensional (3D) food bioprinting technologies for lab-grown muscle food products and their analogues. This innovative approach is a sustainable solution to mitigate the environmental risks associated with climate change caused by the negative impacts of indiscriminative livestock production and industrial aquaculture. This review article explores the adoption of 3D bioprinting modalities to manufacture lab-grown muscle food products and their associated technologies, cells, and bioink formulations. Additionally, various processing techniques, governing the characteristics of bioprinted food products, nutritional compositions, and safety aspects as well as its relevant ethical and social considerations, were discussed. Although promising, further research and development is needed to meet standards and translate into several industrial areas, such as the food and renewable energy industries. In specific, optimization of animal cell culture conditions, development of serum-free media, and bioreactor design are essential to eliminate the risk factors but achieve the unique nutritional requirements and consumer acceptance. In short, the advancement of 3D bioprinting technologies holds great potential for transforming the food industry, but achieving widespread adoption will require continued innovation, rigorous research, and adherence to ethical standards to ensure safety, nutritional quality, and consumer acceptance.

摘要

几十年来,全球对肉类和海鲜产品的需求一直在增加。为了应对这一趋势对环境、社会和经济的影响,用于实验室培育肌肉类食品及其类似物的三维(3D)食品生物打印技术得到了迅猛发展。这种创新方法是一种可持续的解决方案,可减轻因不加区分的畜牧生产和工业化水产养殖的负面影响而导致的气候变化相关环境风险。本文综述探讨了采用3D生物打印方式制造实验室培育的肌肉类食品及其相关技术、细胞和生物墨水配方。此外,还讨论了各种加工技术,这些技术决定了生物打印食品的特性、营养成分、安全方面以及相关的伦理和社会考量。尽管前景广阔,但仍需要进一步的研发以达到标准并转化到几个工业领域,如食品和可再生能源行业。具体而言,优化动物细胞培养条件、开发无血清培养基以及生物反应器设计对于消除风险因素但实现独特的营养需求和消费者接受度至关重要。简而言之,3D生物打印技术的进步在改变食品行业方面具有巨大潜力,但要实现广泛应用将需要持续创新、严谨研究并遵守道德标准,以确保安全性、营养质量和消费者接受度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/e70424187847/nihms-2020268-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/0ec903d224b2/nihms-2020268-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/0e3c0ce6171e/nihms-2020268-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/7ab27ba18613/nihms-2020268-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/e70424187847/nihms-2020268-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/0ec903d224b2/nihms-2020268-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/0e3c0ce6171e/nihms-2020268-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/7ab27ba18613/nihms-2020268-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ebc/11412102/e70424187847/nihms-2020268-f0004.jpg

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2
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Biofabrication. 2023 Nov 20;16(1):012003. doi: 10.1088/1758-5090/ad0b3f.
3
Bioreactors, scaffolds and microcarriers and meat production-current obstacles and potential solutions.生物反应器、支架、微载体与肉类生产——当前的障碍及潜在解决方案
JACS Au. 2025 Jan 22;5(2):411-425. doi: 10.1021/jacsau.4c00796. eCollection 2025 Feb 24.
4
Novel Protein-Rich Bioactive Bioink Stimulates Cellular Proliferation and Response in 3D Bioprinted Volumetric Constructs.新型富含蛋白质的生物活性生物墨水可刺激三维生物打印体积结构中的细胞增殖和反应。
Adv Healthc Mater. 2025 Apr;14(10):e2404470. doi: 10.1002/adhm.202404470. Epub 2025 Feb 25.
Front Nutr. 2023 Sep 6;10:1225233. doi: 10.3389/fnut.2023.1225233. eCollection 2023.
4
Mimicking Wagyu beef fat in cultured meat: Progress in edible bovine adipose tissue production with controllable fatty acid composition.在人造肉中模仿和牛脂肪:可控制脂肪酸组成的食用牛脂肪组织生产进展。
Mater Today Bio. 2023 Jun 30;21:100720. doi: 10.1016/j.mtbio.2023.100720. eCollection 2023 Aug.
5
Three-dimensional food printing: its readiness for a food and nutrition insecure world.三维食品打印:为食品和营养不安全的世界做好准备。
Proc Nutr Soc. 2023 Dec;82(4):468-477. doi: 10.1017/S0029665123003002. Epub 2023 May 15.
6
Cultured meat platform developed through the structuring of edible microcarrier-derived microtissues with oleogel-based fat substitute.利用基于油凝胶的脂肪替代品构建可食用微载体衍生微组织的培养肉平台。
Nat Commun. 2023 May 23;14(1):2942. doi: 10.1038/s41467-023-38593-4.
7
Tissue-like cultured fish fillets through a synthetic food pipeline.类似组织的养殖鱼片通过合成食品管道。
NPJ Sci Food. 2023 May 6;7(1):17. doi: 10.1038/s41538-023-00194-2.
8
Process of drug registration in Israel: the correlation between the number of discussions within the Ministry of Health and postapproval variations by EMA and/or FDA.以色列药品注册流程:卫生部内部讨论次数与 EMA 和/或 FDA 批准后变更之间的相关性。
BMJ Open. 2023 May 4;13(5):e067313. doi: 10.1136/bmjopen-2022-067313.
9
A review on directional muscle cell growth in scaffolding biomaterials with aligned porous structures for cultivated meat production.关于用于培养肉生产的具有定向多孔结构的支架生物材料中定向肌肉细胞生长的综述。
Food Res Int. 2023 Jun;168:112755. doi: 10.1016/j.foodres.2023.112755. Epub 2023 Mar 24.
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