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PEGylated bacteria restore intestinal mucosal barrier.

作者信息

Zu Menghang, Xia Xue, Xiao Bo

机构信息

State Key Laboratory of Resource Insects, College of Sericulture, Textile, and Biomass Sciences, Southwest University, Chongqing 400715, China.

Department of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610054, China.

出版信息

Acta Pharm Sin B. 2024 Sep;14(9):4186-4188. doi: 10.1016/j.apsb.2024.06.016. Epub 2024 Jun 25.

DOI:10.1016/j.apsb.2024.06.016
PMID:39309500
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11413659/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/11413659/c1b962bef198/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/11413659/c1b962bef198/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/11413659/c1b962bef198/gr1.jpg

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本文引用的文献

1
Reinforcement of the intestinal mucosal barrier via mucus-penetrating PEGylated bacteria.通过穿透黏液的聚乙二醇化细菌增强肠道黏膜屏障。
Nat Biomed Eng. 2024 Jul;8(7):823-841. doi: 10.1038/s41551-024-01224-4. Epub 2024 Jun 5.
2
TSP50 Attenuates DSS-Induced Colitis by Regulating TGF-β Signaling Mediated Maintenance of Intestinal Mucosal Barrier Integrity.TSP50 通过调节 TGF-β 信号通路介导的肠道黏膜屏障完整性维持来减轻 DSS 诱导的结肠炎。
Adv Sci (Weinh). 2024 Mar;11(11):e2305893. doi: 10.1002/advs.202305893. Epub 2024 Jan 8.
3
Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity.
溃疡性结肠炎肠道微生物组的多组学分析将脆弱拟杆菌蛋白酶与疾病严重程度联系起来。
Nat Microbiol. 2022 Feb;7(2):262-276. doi: 10.1038/s41564-021-01050-3. Epub 2022 Jan 27.
4
De-escalation of immunomodulator and biological therapy in inflammatory bowel disease.炎症性肠病中免疫调节剂和生物疗法的降级治疗。
Lancet Gastroenterol Hepatol. 2020 Jan;5(1):63-79. doi: 10.1016/S2468-1253(19)30186-4.
5
Sieving through gut models of colonization resistance.筛选定植抵抗的肠道模型。
Nat Microbiol. 2018 Feb;3(2):132-140. doi: 10.1038/s41564-017-0095-1. Epub 2018 Jan 22.
6
Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease.艰难梭菌感染复发患者行粪菌移植后微生物生态学的变化受潜在炎症性肠病的影响。
Microbiome. 2017 May 15;5(1):55. doi: 10.1186/s40168-017-0269-3.
7
Next generation of small molecules in inflammatory bowel disease.炎症性肠病中的新一代小分子药物。
Gut. 2017 Feb;66(2):199-209. doi: 10.1136/gutjnl-2016-312912. Epub 2016 Nov 17.