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[细菌自身调节因子D1制剂对溶壁微球菌细胞膜结构功能的影响]

[Changes in the structural function of the membrane of M. lysodeikticus as affected by preparations of the bacterial autoregulatory factors D1].

作者信息

Kaprel'iants A S, Skrypin V I, El'-Registan G I, Kozlova A N, Ostrovskiĭ D N

出版信息

Prikl Biokhim Mikrobiol. 1985 May-Jun;21(3):378-81.

PMID:3931069
Abstract

Introduction of factors D1 isolated from the culture fluids of B. cereus and Ps. carboxydoflava into cytoplasmic membranes of M. lysodeikticus resulted in a higher microviscosity of the lipid phase. Factor d1 changes the ion permeability of an artificial bilayer membrane as well as reduces the content of free water in the bacterial paste. It is assumed that registered structural changes may result from the interaction of the factor molecules with membrane lipids and be the main reason of changes in the functioning of membrane-bound enzymes and dehydration of the microbial cell as well.

摘要

将从蜡状芽孢杆菌和羧基氧化荧光假单胞菌培养液中分离出的因子D1导入溶壁微球菌的细胞质膜,会导致脂质相的微粘度升高。因子d1会改变人工双层膜的离子通透性,并降低细菌糊剂中的自由水含量。据推测,所记录的结构变化可能是由于因子分子与膜脂相互作用所致,也是膜结合酶功能变化以及微生物细胞脱水的主要原因。

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