Badrov Marija, Gavic Lidia, Seselja Perisin Ana, Zeljezic Davor, Vladislavic Jasen, Puizina Mladinic Ema, Tadin Antonija
Department of Restorative Dental Medicine and Endodontics, University of Split School of Medicine, 21000 Split, Croatia.
Department of Pharmacy, University of Split School of Medicine, 21000 Split, Croatia.
Clin Pract. 2024 Sep 5;14(5):1827-1841. doi: 10.3390/clinpract14050146.
The safety of oral hygiene products is a growing concern, particularly regarding the toxicity of specific ingredients used in their formulations. The purpose of this study was to evaluate the knowledge and attitudes of dentists, physicians, pharmacists, and the general public regarding ingredients in oral hygiene products, especially fluoride. Additionally, this study aimed to identify which ingredients may exhibit potential toxicity based on historical records of any adverse effects being induced by a material/component.
A self-administered questionnaire was used in an online cross-sectional observational study to collect data on sociodemographic characteristics, knowledge of fluoride in dental medicine, fluoride usage practices in oral hygiene products, opinions on ingredient toxicity in oral hygiene products, and personal experiences of adverse reactions to products and their components. The collected data underwent descriptive and regression analyses to reveal patterns and relationships within the dataset.
The study found a moderate overall knowledge level regarding fluoride usage in dentistry among participants (Md = 5.00, IQR 2.50-7.00). Healthcare professionals exhibited significantly higher knowledge scores compared to the general population ( ≤ 0.001), with dental professionals displaying the highest scores. Regarding concerns about the usage of fluoride, the majority of respondents (77.0%) did not express any concerns. Minor concerns included the risk of ingestion (6.0%) and dental fluorosis (4.6%). Among the other ingredients in oral hygiene products, respondents named alcohol as the most toxic ingredient (70.3%), followed by artificial colors (53.1%), artificial sweeteners (50.4%), and parabens (50.1%). It is noteworthy that the majority of participants (61.6%) stated that they had never experienced any side effects associated with the use of oral hygiene products.
This study underscores disparities in fluoride knowledge between healthcare professionals and the general population in Croatia, with dental experts exhibiting a superior understanding. Despite lingering misconceptions about fluoride content and potential toxicity, the majority of participants acknowledge its oral health benefits and use fluoride products regularly.
口腔卫生产品的安全性日益受到关注，尤其是其配方中特定成分的毒性问题。本研究的目的是评估牙医、医生、药剂师和普通公众对口腔卫生产品成分，特别是氟化物的了解和态度。此外，本研究旨在根据某种材料/成分引起不良反应的历史记录，确定哪些成分可能具有潜在毒性。
在一项在线横断面观察研究中，使用自填式问卷收集有关社会人口学特征、牙科医学中氟化物知识、口腔卫生产品中氟化物使用习惯、对口腔卫生产品成分毒性的看法以及对产品及其成分不良反应的个人经历的数据。对收集到的数据进行描述性和回归分析，以揭示数据集中的模式和关系。
研究发现参与者对牙科中氟化物使用的总体了解程度中等（中位数 = 5.00，四分位距 2.50 - 7.00）。与普通人群相比，医疗保健专业人员的知识得分显著更高（≤ 0.001），牙科专业人员得分最高。关于对氟化物使用的担忧，大多数受访者（77.0%）没有表达任何担忧。较小的担忧包括摄入风险（6.0%）和氟斑牙（4.6%）。在口腔卫生产品的其他成分中，受访者将酒精列为毒性最大的成分（70.3%），其次是人工色素（53.1%）、人工甜味剂（50.4%）和对羟基苯甲酸酯（50.1%）。值得注意的是，大多数参与者（61.6%）表示他们从未经历过与使用口腔卫生产品相关的任何副作用。
本研究强调了克罗地亚医疗保健专业人员和普通人群在氟化物知识方面的差异，牙科专家表现出更优越的理解。尽管对氟化物含量和潜在毒性仍存在误解，但大多数参与者认可其对口腔健康的益处并定期使用含氟产品。
