van der Straaten Merel, van den Hoogen Agnes, Tataranno Maria-Luisa, van Berkel Catelijn J M, Schmit Lisa, Jeekel Hans, Hennink Annelies, Benders Manon, Dudink Jeroen
Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
Utrecht University, Utrecht, The Netherlands.
Pediatr Res. 2024 Sep 23. doi: 10.1038/s41390-024-03586-6.
Premature birth heightens neurodevelopmental risks, theorized to partly stem from altered sensory inputs and disrupted sleep patterns. Modifying the acoustic milieu through music intervention (MI) offers promise to improve neonatal comfort, reduce sleep disturbances, and stabilize physiological parameters. This study explores the impact of non-pharmacological MI on these health indicators within the Neonatal Intensive Care Unit (NICU).
A single-blinded RCT was conducted. Premature infants (34 > GA > 29 wks) were randomly assigned to either receive 8 min of daily MI or placebo for up to 15 days. Validated behavioral comfort scores were visually obtained by a blinded observer before and after intervention. Additionally, physiological signs (HR, RR, SatO2) were recorded. Differences between the groups were analyzed using χ² tests and t-tests.
In total 56 preterm infants were included. After intervention, comfort levels increased significantly in the MI compared to placebo group (p = 0.000). Neonates receiving MI transitioned from wakefulness to a state of sleep significantly more compared to placebo (p = 0.002). Physiological parameters remained stable.
This study adds to existing literature demonstrating that a music intervention in a NICU setting can enhance comfort and sleep of premature infants without adversely affecting physiological parameters.
The study demonstrates that music interventions (MI) in a Neonatal Intensive Care Unit (NICU) setting can significantly increase comfort levels and positively impact the sleep of premature infants without negatively impacting their physiological parameters. This research increases evidence for non-pharmacological interventions, specifically music, as beneficial for the well-being of premature infants in NICU settings. It replicates and expands upon previous methodological designs, providing more robust evidence of MI's positive effects on this vulnerable population. The positive outcomes of music intervention could influence hospital policies by integrating non-pharmacological practices into standard neonatal care protocols to enhance developmental support for premature infants.
早产会增加神经发育风险,理论上部分源于感觉输入改变和睡眠模式紊乱。通过音乐干预(MI)改变声学环境有望改善新生儿舒适度、减少睡眠干扰并稳定生理参数。本研究探讨了非药物性音乐干预对新生儿重症监护病房(NICU)内这些健康指标的影响。
进行了一项单盲随机对照试验。将早产婴儿(34周>孕龄>29周)随机分为两组,一组每天接受8分钟的音乐干预,另一组接受安慰剂,干预时间长达15天。由一位盲法观察者在干预前后通过视觉获得经过验证的行为舒适度评分。此外,记录生理体征(心率、呼吸频率、血氧饱和度)。使用χ²检验和t检验分析两组之间的差异。
共纳入56名早产婴儿。干预后,与安慰剂组相比,音乐干预组的舒适度显著提高(p = 0.000)。与安慰剂组相比,接受音乐干预的新生儿从清醒状态转变为睡眠状态的比例显著更高(p = 0.002)。生理参数保持稳定。
本研究补充了现有文献,表明在新生儿重症监护病房环境中进行音乐干预可以提高早产婴儿的舒适度和睡眠质量,而不会对生理参数产生不利影响。
该研究表明,在新生儿重症监护病房(NICU)环境中进行音乐干预(MI)可以显著提高舒适度,并对早产婴儿的睡眠产生积极影响,而不会对其生理参数产生负面影响。这项研究增加了非药物干预(特别是音乐)对NICU环境中早产婴儿健康有益的证据。它重复并扩展了以前的方法设计,为音乐干预对这一脆弱人群的积极影响提供了更有力的证据。音乐干预的积极结果可能会影响医院政策,将非药物措施纳入标准新生儿护理方案,以加强对早产婴儿的发育支持。