Basher H A, Fowler D R, Seaman A, Woodbine M
Zentralbl Bakteriol Mikrobiol Hyg A. 1985 May;259(3):351-8. doi: 10.1016/s0176-6724(85)80037-7.
Progesterone was examined for action on the virulence of Listeria monocytogenes and the toxicity of its haemolysin. Progesterone at concentrations between 5 and 20 micrograms/ml reduced the numbers of L. monocytogenes over the first two hours of growth. Virulence and haemolysin toxicity were assessed using the allantoic sac route of inoculation into embryonated hens eggs. Increasing the concentrations of progesterone in the culture medium resulted in a decrease in the mortality of chick embryos inoculated with either organisms, or cell-free extracts or purified haemolysin. Progesterone had no effect on the lethality of pre-formed haemolysin.
研究了孕酮对单核细胞增生李斯特菌毒力及其溶血素毒性的作用。浓度在5至20微克/毫升之间的孕酮在生长的前两小时内减少了单核细胞增生李斯特菌的数量。使用尿囊接种途径将病毒接种到受精母鸡的鸡蛋中，评估其毒力和溶血素毒性。增加培养基中孕酮的浓度会导致接种了活菌体、无细胞提取物或纯化溶血素的鸡胚死亡率降低。孕酮对预先形成的溶血素的致死性没有影响。
