Bernáth S, Pitron M
Veterinary and Food Control Service, Control Institute for Veterinary Biologicals and Pharmaceuticals, Budapest.
Acta Microbiol Hung. 1989;36(4):373-6.
For studying the relationship between their haemolysin producing capacity and pathogenicity on mice, 12 Listeria strains were investigated, and 9 of them were reinvestigated one year later. Haemolysin production was measured on 51Cr-labelled sheep erythrocytes and the 50% haemolysis-inducing dilution of the bacterial suspensions was calculated. Pathogenicity of the strains was estimated by intraperitoneal injection of mice. In both experimental series the correlation coefficients were calculated (r = 0.408, t = 1.41 and r = 0.163, t = 0.43). Using this experimental system, no correlation existed between the haemoysin producing capacity and mouse-pathogenicity of these strains.
为研究12株李斯特菌产生溶血素的能力与其对小鼠致病性之间的关系，对这些菌株进行了调查，其中9株在一年后再次进行调查。采用51Cr标记的绵羊红细胞检测溶血素的产生情况，并计算细菌悬液诱导50%溶血的稀释度。通过腹腔注射小鼠评估菌株的致病性。在两个实验系列中均计算了相关系数（r = 0.408，t = 1.41和r = 0.163，t = 0.43）。利用该实验系统，这些菌株产生溶血素的能力与对小鼠的致病性之间不存在相关性。
