Tsai Wan-Hsun, Kang Bor-Hwang
Department of Otorhinolaryngology, Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
School of Medicine, National Defense Medical Center, Taipei, Taiwan.
SAGE Open Med Case Rep. 2024 Sep 20;12:2050313X241275339. doi: 10.1177/2050313X241275339. eCollection 2024.
Pleomorphic adenoma is a benign tumor and the most common salivary gland neoplasm. Metastasizing pleomorphic adenoma shares histological characteristics with pleomorphic adenoma but exhibits malignant behavior, including local lymph node involvement and/or distant metastasis. Several potential risk factors for metastasizing pleomorphic adenoma have been identified, some of which are associated with incomplete tumor clearance due to inadequate surgical techniques used in the treatment of primary pleomorphic adenoma. Here, we present a rare case of metastasizing pleomorphic adenoma originating from the parotid gland and describe its clinical features. The patient was a 75-year-old female with a surgical history of enucleation of a pleomorphic adenoma in the left parotid gland. Total parotidectomy and left neck dissection were performed for the left parotid tumor this time, and the patient attended one postoperative outpatient visit but subsequently was lost to follow-up.
多形性腺瘤是一种良性肿瘤，也是最常见的涎腺肿瘤。转移性多形性腺瘤与多形性腺瘤具有相同的组织学特征，但表现出恶性行为，包括局部淋巴结受累和/或远处转移。已确定了几种转移性多形性腺瘤的潜在危险因素，其中一些与原发性多形性腺瘤治疗中手术技术不足导致肿瘤清除不完全有关.在此，我们报告一例罕见的起源于腮腺的转移性多形性腺瘤病例，并描述其临床特征。该患者为75岁女性，有左侧腮腺多形性腺瘤摘除手术史。此次对左侧腮腺肿瘤行腮腺全切除术及左侧颈淋巴结清扫术.患者术后曾到门诊复诊一次，但随后失访。
