Su Haodong, Ye Tongtong, Cao Songyan, Hu Chunyan
College of Humanities, Anhui Science and Technology University, Chuzhou, China.
Psychological Education Research Department, Anhui Science and Technology University, Chuzhou, China.
Front Psychol. 2024 Sep 9;15:1416222. doi: 10.3389/fpsyg.2024.1416222. eCollection 2024.
Compulsion stands as a central symptom of drug addiction; however, only a small fraction of individuals who use drugs exhibit compulsive characteristics. Differences observed in Sign-trackers (ST) and Goal-trackers (GT) during Pavlovian conditioning may shed light on individual variances in drug addiction. Here, we focus on the behavioral attributes, formation processes, and neural mechanisms underlying ST and how they drive addiction toward compulsivity in humans. We will explore addiction from three interconnected levels: individual personality traits, social factors, and neurobiology. Furthermore, we distinguish between the processes of sensitization and habituation within ST. These nuanced distinctions across various aspects of addiction will contribute to our understanding of the addiction development process and the formulation of targeted preventive strategies.
强迫行为是药物成瘾的核心症状；然而，只有一小部分吸毒者表现出强迫特征。在巴甫洛夫条件反射过程中观察到的信号追踪者（ST）和目标追踪者（GT）之间的差异，可能有助于揭示药物成瘾中的个体差异。在这里，我们关注ST的行为属性、形成过程和神经机制，以及它们如何在人类中促使成瘾发展为强迫行为。我们将从三个相互关联的层面探讨成瘾问题：个体人格特质、社会因素和神经生物学。此外，我们还区分了ST中的敏感化和习惯化过程。这些成瘾各个方面的细微差别，将有助于我们理解成瘾发展过程，并制定有针对性的预防策略。
