Brooks C D, Nelson A L, Metzler C
Ann Allergy. 1985 Oct;55(4):557-62.
Sixty-two volunteer hay fever patients participated in a 2-week trial which examined the protective effect of the cyclooxygenase-inhibiting drug flurbiprofen. The drug suppressed symptom severity significantly, though it was not as protective as the antihistamine also employed in the trial. Flurbiprofen's effects suggests that prostaglandin release may contribute to the symptoms of allergic rhinitis.
62名花粉症志愿者参与了一项为期两周的试验,该试验检测了环氧化酶抑制药物氟比洛芬的保护作用。该药物显著抑制了症状的严重程度,尽管其保护作用不如试验中同时使用的抗组胺药。氟比洛芬的作用表明,前列腺素的释放可能导致过敏性鼻炎的症状。