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31 例行全内镜脊柱手术患者的无创颅内压谱。

Noninvasive intracranial pressure profile in 31 patients submitted to fullendoscopic spine surgery.

机构信息

Universidade de São Paulo - Faculdade de Medicina de Ribeirão Preto - Departmento de Cirurgia e Anatomia - Ribeirão Preto (SP) - Brazil.

出版信息

Acta Cir Bras. 2024 Sep 20;39:e396424. doi: 10.1590/acb396424. eCollection 2024.

DOI:10.1590/acb396424
PMID:39319901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11414522/
Abstract

PURPOSE

Full-endoscopic spine surgery (FESS) is associated with specific complications, possibly linked to increased intracranial pressure (ICP) resulting from continuous saline infusion into the epidural space. This study aimed to assess the impact of saline irrigation and its correlation with noninvasively obtained ICP waveform changes.

METHODS

Patients undergoing FESS between January 2019 and November 2020 were included. Noninvasive ICP (n-ICP) monitoring utilized an extracranial strain sensor generating ICP waveforms, from which parameters P2/P1 ratio and time to peak (TTP) values were derived and correlated to irrigation and vital parameters. Documentation occurred at specific surgical intervals (M0-preoperatively; M1 to M4-intraoperatively; M5-postoperatively). Mixed-model analysis of variance and multiple comparisons tests were applied, with M0 as the baseline.

RESULTS

Among 31 enrolled patients, three experienced headaches unrelated to increased ICP at M5. The P2/P1 ratio and TTP decreased during surgery (p < 0.001 and p < 0.004, respectively). Compared to baseline, P2/P1 ratio and vital parameters remained significantly lower at M5. No significant differences were observed for fluid parameters throughout surgery.

CONCLUSIONS

This study demonstrated a decline in the n-ICP parameters after anesthetic induction despite the anticipated increase in ICP due to constant epidural irrigation. The n-ICP parameters behaved independently of fluid parameters, suggesting a potential protective effect of anesthesia.

摘要

目的

全内镜脊柱手术(FESS)与特定并发症相关,这些并发症可能与由于持续向硬膜外腔注入生理盐水而导致的颅内压(ICP)升高有关。本研究旨在评估盐水冲洗的影响及其与非侵入性获得的 ICP 波形变化的相关性。

方法

纳入 2019 年 1 月至 2020 年 11 月期间接受 FESS 的患者。非侵入性 ICP(n-ICP)监测使用外部颅内应变传感器生成 ICP 波形,从中得出 P2/P1 比值和波峰时间(TTP)值,并与冲洗和生命参数相关联。记录发生在特定手术间隔(M0-术前;M1 到 M4-术中;M5-术后)。采用混合模型方差分析和多重比较检验,以 M0 作为基线。

结果

在 31 名入组患者中,有 3 名患者在 M5 时出现与 ICP 升高无关的头痛。术中 P2/P1 比值和 TTP 降低(p<0.001 和 p<0.004)。与基线相比,M5 时 P2/P1 比值和生命参数仍显著降低。整个手术过程中,液体参数没有显著差异。

结论

尽管由于持续硬膜外冲洗预计 ICP 会升高,但本研究在麻醉诱导后显示 n-ICP 参数下降。n-ICP 参数与液体参数无关,提示麻醉可能具有潜在的保护作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/c7bb797db98e/1678-2674-acb-39-e396424-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/7b197eba95fc/1678-2674-acb-39-e396424-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/b7e02983db75/1678-2674-acb-39-e396424-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/4b876faadd31/1678-2674-acb-39-e396424-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/699a85e93273/1678-2674-acb-39-e396424-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/c7bb797db98e/1678-2674-acb-39-e396424-gf05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/7b197eba95fc/1678-2674-acb-39-e396424-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/b7e02983db75/1678-2674-acb-39-e396424-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/4b876faadd31/1678-2674-acb-39-e396424-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/699a85e93273/1678-2674-acb-39-e396424-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c408/11414522/c7bb797db98e/1678-2674-acb-39-e396424-gf05.jpg

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Nutrients. 2022 Jun 15;14(12):2472. doi: 10.3390/nu14122472.
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Intracranial Compliance Assessed by Intracranial Pressure Pulse Waveform.通过颅内压脉搏波形评估颅内顺应性。
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