Yamamoto Takahiro, Kimura Naoyuki, Hori Daijiro, Mieno Makiko, Shiraishi Manabu, Okamura Homare, Kawahito Koji, Yamaguchi Atsushi
Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Department of Surgery, Division of Cardiovascular Surgery, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke, 329-0498, Japan.
Surg Today. 2025 Mar;55(3):414-424. doi: 10.1007/s00595-024-02919-6. Epub 2024 Sep 25.
To investigate the morphological characteristics and operative outcomes of acute type A aortic dissection (ATAAD) in patients with aortic arch variants.
Of 616 patients with ATAAD, 97 (15.7%) had aortic arch variants, including bovine aortic arch (BAA, n = 66), isolated left vertebral artery (ILVA, n = 25), and aberrant subclavian artery (ASA, n = 6). The characteristics and outcomes were compared between the normal branching group (control, n = 519) and the total/individual arch variant groups.
Compared to the control group, arch entry was more prevalent in the BAA (18.5% vs. 31.8%) and ILVA groups (44%) (both, P < 0.05), and right common carotid arterial occlusion was less common in the arch variant group (6.7% vs. 0%, P = 0.017). The in-hospital mortality (9.2% vs. 9.3%), new-onset stroke (7.3% vs. 7.2%), and 5-year survival (81.7% vs. 78.8%) did not differ markedly between the control and arch variant groups. Arch repair was performed in 28.9% (28/97) of the arch variant group using 3-4 vessel antegrade cerebral perfusion, with 3.8% in-hospital mortality and a 15.4% stroke rate, which were comparable to those of the control group.
Aortic arch variants may influence tear location and involvement of the supra-arch vessels but may not affect postoperative outcomes.
探讨主动脉弓变异患者急性A型主动脉夹层(ATAAD)的形态学特征及手术效果。
在616例ATAAD患者中,97例(15.7%)存在主动脉弓变异,包括牛主动脉弓(BAA,n = 66)、孤立左椎动脉(ILVA,n = 25)和迷走锁骨下动脉(ASA,n = 6)。比较正常分支组(对照组,n = 519)与总/各型主动脉弓变异组的特征及手术效果。
与对照组相比,BAA组(18.5%对31.8%)和ILVA组(44%)的主动脉弓入口更为常见(均P < 0.05),且主动脉弓变异组右颈总动脉闭塞较少见(6.7%对0%,P = 0.017)。对照组与主动脉弓变异组的住院死亡率(9.2%对9.3%)、新发卒中(7.3%对7.2%)和5年生存率(81.7%对78.8%)差异无统计学意义。主动脉弓变异组28.9%(28/97)采用3 - 4支血管顺行脑灌注进行主动脉弓修复,住院死亡率为3.8%,卒中发生率为15.4%,与对照组相当。
主动脉弓变异可能影响撕裂部位及弓上血管受累情况,但不影响术后效果。