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评估与复杂切口疝修补术中腹膜瓣修补相关的风险因素 - 327 例回顾性研究。

Evaluation of risk factors associated with the peritoneal flap hernioplasty for complex incisional hernia repair - a retrospective review of 327 cases.

机构信息

Department of Surgery, University Hospital of Southern Denmark, Aabenraa, 6200, Denmark.

Department of Upper GI Surgery, Royal Infirmary of Edinburgh, Edinburgh, Scotland.

出版信息

Hernia. 2024 Dec;28(6):2301-2309. doi: 10.1007/s10029-024-03162-1. Epub 2024 Sep 25.

Abstract

BACKGROUND

Repair of large incisional hernias is challenging, and the risks of postoperative complications have been associated with obesity, smoking, and diabetes. The present study was conducted to determine the impact of these risk factors on short and long-term outcomes following the repair with the peritoneal flap hernioplasty (PFH).

METHODS

Three hundred twenty-seven patients undergoing PFH for incisional hernia repair were identified. Patient demographics and clinical data were recorded. Patients presenting signs of complications were assessed during a visit to the outpatient clinic. A multivariable regression analysis was performed to evaluate the association between BMI, smoking and diabetes, and postoperative complications.

RESULTS

The study included 157 males (48.0%) and 170 females (52.0%). Median BMI was 30.9 kg/m. Diabetes was present in 13.8% of patients. 23.2% were active smokers. The recurrence rate was 2.4%. The odds ratios for postoperative complications were increased by 9% per BMI unit (P < 0.01), due predominantly to a rise in superficial wound infections (P < 0.01) and seroma production (P = 0.07). The adjusted odds ratio increased fourfold in patients with BMI > 40 kg/m (P = 0.06).

CONCLUSION

Incisional hernia repair with the PFH technique is associated with a low risk of short and long-term complications. The risk is associated with obesity and significantly increased in patients with a BMI exceeding 40 kg/m, where a fourfold increase was observed predominantly due to seroma and superficial wound infections. The recurrence rate was 2.4% and was unaltered across BMI categories. No association was established between smoking, diabetes, and the risk of all-cause complications.

摘要

背景

修复大型切口疝具有挑战性,并且术后并发症的风险与肥胖、吸烟和糖尿病有关。本研究旨在确定这些危险因素对使用腹膜瓣修补术(PFH)修复后短期和长期结果的影响。

方法

确定了 327 例接受 PFH 治疗切口疝修复的患者。记录患者的人口统计学和临床数据。在门诊就诊时评估出现并发症迹象的患者。进行多变量回归分析,以评估 BMI、吸烟和糖尿病与术后并发症之间的关联。

结果

该研究包括 157 名男性(48.0%)和 170 名女性(52.0%)。中位数 BMI 为 30.9kg/m2。糖尿病患者占 13.8%。23.2%为活跃吸烟者。复发率为 2.4%。BMI 每增加 1 个单位,术后并发症的优势比增加 9%(P<0.01),主要是由于浅表伤口感染(P<0.01)和血清肿形成(P=0.07)增加。BMI>40kg/m2 的患者调整后的优势比增加了四倍(P=0.06)。

结论

使用 PFH 技术修复切口疝与短期和长期并发症的风险低相关。风险与肥胖有关,在 BMI 超过 40kg/m2 的患者中显著增加,其中观察到四倍的增加主要是由于血清肿和浅表伤口感染。复发率为 2.4%,且在 BMI 分类中无变化。吸烟、糖尿病与所有原因并发症的风险之间未建立关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3890/11530506/4b7293e2f32c/10029_2024_3162_Fig1_HTML.jpg

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