Martínez de Victoria E, López M A
Rev Esp Fisiol. 1979 Jun;35(2):181-5.
Superior cervical ganglion stimulation significantly increases both, flow and amylase activity of saliva. Stimulation provokes two markedly different periods of flow: during the first half, flow is very high and differs significantly from the flow of the second half which closely resembles the one previous to stimulation. Alpha-adrenergic blocking agents, when administered intravenously, abolish the hypersecretion induced by sympathetic stimulation; beta-adrenergic blocking agents do not. These facts strengthen the hypothesis that alpha-adrenoceptors are most important in fluid secretion. The infusion of epinephrine acts similarly on cervical ganglion stimulation, but it differs because of its more diffuse effects and deeper cardiovascular alterations. Isoproterenol, after a long latency period, slightly increases salivary flow, which seemingly indicates that beta-adrenoceptors are involved in the fluid secretory processes although in a lesser degree than alpha-adrenoceptors.
颈上神经节刺激可显著增加唾液的流量和淀粉酶活性。刺激引发两个明显不同的唾液分泌期:在前半期,分泌量非常高,与后半期的分泌量有显著差异,后半期的分泌量与刺激前的分泌量非常相似。静脉注射α-肾上腺素能阻断剂可消除交感神经刺激引起的分泌过多;而β-肾上腺素能阻断剂则无此作用。这些事实强化了α-肾上腺素能受体在液体分泌中最为重要的假说。肾上腺素的输注对颈神经节刺激的作用相似,但因其作用更广泛且心血管改变更深而有所不同。异丙肾上腺素在较长的潜伏期后,可轻微增加唾液流量,这似乎表明β-肾上腺素能受体参与了液体分泌过程,尽管程度低于α-肾上腺素能受体。