Université de Bordeaux, UFR des Sciences Odontologiques, Center for Rare Oral and Dental Diseases, CCMR O-Rares, C.H.U. de Bordeaux, Bordeaux, France.
School of Dental Medicine, East Carolina University, Greenville, North Carolina, USA.
Monogr Oral Sci. 2024;32:166-172. doi: 10.1159/000538885. Epub 2024 Jul 1.
The development of the human dentition is susceptible to disruption owing to its intricate and delicate nature, encompassing variations in tooth number, anatomical configuration, and the characteristics of enamel, dentine, and cementum. This chapter will specifically address the prevalent defect of molar incisor hypomineralisation (MIH), which can impose a significant treatment burden on individuals. MIH is linked to deleterious alterations in the properties of affected enamel, which can lead to rapid enamel breakdown and carious lesion formation in those at a heightened caries risk. In addition, MIH is associated with tooth sensitivity, dental anxiety, difficulty eating, aesthetic concerns, and negative influence during the child's psychological growth, especially when the MIH is severe. Regarding dental caries, it is essential to note that MIH does not directly increase the risk of caries. However, MIH can alter the way the caries process manifests by creating niches where biofilm can accumulate, complicating oral cleaning efforts. Additionally, MIH adversely modifies the physicochemical properties of enamel, influencing how this "hardest of tissues" responds to cariogenic challenges.
人类牙齿的发育很容易受到干扰,因为它具有复杂而精细的性质,包括牙齿数量、解剖结构以及釉质、牙本质和牙骨质的特征的变化。本章将专门讨论常见的磨牙-切牙釉质发育不全(MIH)缺陷,它会给个体带来重大的治疗负担。MIH 与受影响釉质特性的有害变化有关,这可能导致在高龋风险人群中快速的釉质破坏和龋齿病变形成。此外,MIH 还与牙齿敏感、牙科焦虑、进食困难、美学问题以及儿童心理成长期间的负面影响有关,尤其是当 MIH 较为严重时。关于龋齿,需要注意的是,MIH 不会直接增加龋齿的风险。然而,MIH 可以通过创造生物膜可以积累的小窝,从而改变龋齿过程表现的方式,使口腔清洁变得复杂。此外,MIH 还会改变釉质的物理化学性质,影响这个“最坚硬的组织”对致龋挑战的反应。