2023 年越南出现的猴痘病毒 C.1 亚谱系引起社区传播。
Emerging Monkeypox Virus Sublineage C.1 Causing Community Transmission, Vietnam, 2023.
出版信息
Emerg Infect Dis. 2024 Nov;30(11):2385-2390. doi: 10.3201/eid3011.240729. Epub 2024 Sep 25.
Abstract
We studied a community cluster of 25 mpox cases in Vietnam caused by emerging monkeypox virus sublineage C.1 and imported into Vietnam through 2 independent events; 1 major cluster carried a novel APOBEC3-like mutation. Three patients died; all had advanced HIV co-infection. Viral evolution and its potential consequences should be closely monitored.
摘要
我们研究了在越南发生的一起由新兴猴痘病毒亚谱系 C.1 引起的 25 例猴痘病例的社区集群，该病毒是通过 2 个独立事件传入越南的；1 个主要集群携带一种新的 APOBEC3 样突变。3 名患者死亡；所有患者均合并有晚期 HIV 感染。应密切监测病毒的进化及其潜在后果。
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