Pearce J R, Powell H S, Chandler F W, Visvesvara G S
J Am Vet Med Assoc. 1985 Nov 1;187(9):951-2.
A natural infection of Acanthamoeba castellani, a free-living ameba, was determined to be the cause of acute, hemorrhagic, necrotizing amebic meningoencephalitis in a dog. This case is unique because previous reports of infection by the Acanthamoeba spp in dogs have not indicated its presence in the brain. Naturally developing meningoencephalitis by Acanthamoeba spp in the dog may have a pathogenesis similar to that of human beings. The ameba in this case also was observed in the lungs and kidneys, which are believed to be the primary sites of lesions in human beings that develop amebic meningoencephalitis from Acanthamoeba spp.
自由生活的阿米巴——卡氏棘阿米巴的自然感染被确定为一只狗急性、出血性、坏死性阿米巴脑膜脑炎的病因。该病例很独特，因为先前关于犬棘阿米巴属感染的报告未表明其在脑部存在。犬自然发生的棘阿米巴属脑膜脑炎可能具有与人类相似的发病机制。在该病例中，还在肺和肾中观察到了这种阿米巴，而肺和肾被认为是人类因棘阿米巴属发生阿米巴脑膜脑炎时的主要病变部位。
