Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases coconstructed by Henan province & Education Ministry of P.R. China, Henan University of Chinese Medicine, Zhengzhou, China.
Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, China.
J Evid Based Med. 2024 Sep;17(3):654-666. doi: 10.1111/jebm.12650. Epub 2024 Sep 25.
This study aimed to develop and evaluate the efficacy and safety of Supine Daoyin, a TCM PR technique, in hospitalized patients with AECOPD.
This is a multicenter, prospective, randomized, controlled trial involving AECOPD inpatients recruited from April 2021 to December 2023 in five tertiary hospitals in China. Participants were randomly assigned to 14 days of Supine Daoyin group or control group and evaluated at days 3, 7, and 14 (posttreatment). The primary outcomes were LOS and CCQ and secondary outcomes were 6MWD, 30-STS, BI, Borg CR10, time on mechanical ventilation, SGRQ, mCOPD-PRO, and mESQ-COPD.
Out of 369 participants screened, 228 were randomly assigned (Supine Daoyin group: n = 114; control group: n = 114). For primary outcomes, there was no significant between-group difference in LOS (p > 0.05), but for CCQ the Supine Daoyin was superior to control at days 7 (p < 0.01) and 14 (p < 0.01). For secondary outcomes, Supine Daoyin groups showed robust and superior improvements in 6MWD, 30-STS, BI, Borg CR10, SGRQ, mCOPD-PRO, and mESQ-COPD (all p < 0.05), but for time on mechanical ventilation there was no significant difference in two groups (p > 0.05).
Supine Daoyin, a novel TCM PR technique, demonstrates safety and efficacy for AECOPD inpatients, yielding clinically meaningful improvements in health status, exercise capacity, and quality of life. This study offers a viable PR option for AECOPD patients with severe symptoms and limited mobility.
本研究旨在开发和评估仰卧导引，一种中医物理康复技术，在 AECOPD 住院患者中的疗效和安全性。
这是一项多中心、前瞻性、随机、对照试验，纳入了 2021 年 4 月至 2023 年 12 月期间中国五家三级医院的 AECOPD 住院患者。参与者被随机分配到 14 天的仰卧导引组或对照组，并在第 3、7 和 14 天（治疗后）进行评估。主要结局是 LOS 和 CCQ，次要结局是 6MWD、30-STS、BI、Borg CR10、机械通气时间、SGRQ、mCOPD-PRO 和 mESQ-COPD。
在 369 名筛选的参与者中，有 228 名被随机分配（仰卧导引组：n=114；对照组：n=114）。对于主要结局，LOS 两组间无显著差异（p>0.05），但 CCQ 在第 7 天（p<0.01）和第 14 天（p<0.01）时仰卧导引优于对照组。对于次要结局，仰卧导引组在 6MWD、30-STS、BI、Borg CR10、SGRQ、mCOPD-PRO 和 mESQ-COPD 方面表现出显著且优越的改善（均 p<0.05），但两组在机械通气时间方面无显著差异（p>0.05）。
仰卧导引，一种新的中医物理康复技术，对 AECOPD 住院患者安全有效，可显著改善健康状况、运动能力和生活质量。对于症状严重且活动受限的 AECOPD 患者，本研究提供了一种可行的物理康复选择。
