Garland D E, Hanscom D A, Keenan M A, Smith C, Moore T
J Bone Joint Surg Am. 1985 Oct;67(8):1261-9.
Lesions of heterotopic ossification were excised from thirty-seven joints in twenty-three adults who had had injuries to the brain. The lesions were excised from twenty-three elbows, twelve hips, and two shoulders. Patients were retrospectively divided into five categories according to the neural residua (cognitive and physical deficits). The patients in Class I (minimum cognitive and physical disability) and patients in Class II (minimum cognitive disability and moderate physical disability) who had fair or good selective control of the affected extremity had the best prognosis for maintaining the range of motion resulting from resecting the lesion and improving function postoperatively. They also had a low incidence of recurrence of the lesion. Seven of the nine elbows and eight of the eight hips in patients in these classes had successful results. All three of the patients in Class V (severe cognitive and physical deficits) who had a lesion of the hip and all eight of the patients in Class V with poor selective control had a poor result. In the twenty-five joints for which adequate follow-up radiographs were available to determine if the lesion recurred, fourteen recurrences were identified (56 per cent). Eleven of these patients were considered to have a poor result. Nine of the fourteen recurrences occurred in patients in Class V. Radiographic evidence of the maturity of the lesion and a normal level of alkaline phosphatase were of limited importance in predicting a low rate of recurrence. The over-all complications included four superficial infections and no instances of osteomyelitis.(ABSTRACT TRUNCATED AT 250 WORDS)
从23名脑部受伤的成年人的37个关节处切除异位骨化病灶。这些病灶分别从23个肘部、12个髋部和2个肩部切除。根据神经残留情况(认知和身体缺陷)将患者回顾性地分为五类。I类患者(认知和身体残疾程度最低)和II类患者(认知残疾程度最低且身体残疾程度中等),其对患侧肢体有良好或较好的选择性控制,在切除病灶后维持活动范围和术后改善功能方面预后最佳。病灶复发率也较低。这些类别的患者中,9个肘部中的7个和8个髋部中的8个手术结果成功。V类患者(严重认知和身体缺陷)中,所有3名髋部有病灶的患者以及所有8名选择性控制较差的患者手术结果均不佳。在有足够随访X光片可确定病灶是否复发的25个关节中,发现14个复发(56%)。其中11名患者被认为手术结果不佳。14个复发病例中有9个发生在V类患者中。病灶成熟的影像学证据和碱性磷酸酶正常水平在预测低复发率方面的重要性有限。总体并发症包括4例浅表感染,无骨髓炎病例。(摘要截短至250字)