Garland D E, Blum C E, Waters R L
J Bone Joint Surg Am. 1980 Oct;62(7):1143-6.
The records of 496 adult patients who sustained severe injuries to the head were reviewed retrospectively in order to reveal the incidence and location of heterotopic ossification. All traumatized joints were excluded from the study. Clinically significant heterotopic bone causing pain and a decrease in the range of motion of the adjacent joint was identified in 100 joints in fifty-seven patients (11 per cent). All fifty-seven patients had some residual spasticity, although the spasticity was not always present about the involved joint. Twenty-seven patients had monoarticular involvement while thirty patients had involvement of more than one joint. Forty-four hips, twenty-seven shoulders, twenty-six elbows, and three knees had heterotopic ossification. Complete ankylosis (16 per cent of all joints) developed in eight elbows, six hips, and two shoulders.
为了揭示异位骨化的发生率和位置,对496例头部受重伤的成年患者的记录进行了回顾性研究。所有受伤的关节均被排除在研究之外。在57例患者的100个关节中发现了临床上显著的异位骨化,导致疼痛并使相邻关节活动范围减小(11%)。所有57例患者均有一定程度的残余痉挛,尽管痉挛并不总是出现在受累关节周围。27例患者为单关节受累,30例患者为多个关节受累。44个髋关节、27个肩关节、26个肘关节和3个膝关节出现了异位骨化。8个肘关节、6个髋关节和2个肩关节出现了完全强直(占所有关节的16%)。