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Learning from Negative Trials for Diabetic Kidney Disease.

作者信息

Touyz Rhian M

机构信息

Department of Medicine, Department of Family Medicine, Research Institute of McGill University Health Centre, McGill University, Montreal, Canada.

出版信息

J Am Soc Nephrol. 2024 Nov 1;35(11):1463-1465. doi: 10.1681/ASN.0000000511. Epub 2024 Sep 26.

DOI:10.1681/ASN.0000000511
PMID:39325537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11543022/
Abstract
摘要

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本文引用的文献

1
Vascular Endothelial Growth Factor-B Blockade with CSL346 in Diabetic Kidney Disease: A Phase 2A Randomized Controlled Trial.CSL346阻断血管内皮生长因子-B治疗糖尿病肾病：一项2A期随机对照试验
J Am Soc Nephrol. 2024 Nov 1;35(11):1546-1557. doi: 10.1681/ASN.0000000000000438. Epub 2024 Aug 16.
2
Oxidative Stress Induced by Lipotoxicity and Renal Hypoxia in Diabetic Kidney Disease and Possible Therapeutic Interventions: Targeting the Lipid Metabolism and Hypoxia.脂毒性和肾缺氧在糖尿病肾病中诱导的氧化应激及可能的治疗干预措施：针对脂质代谢和缺氧
Antioxidants (Basel). 2023 Dec 6;12(12):2083. doi: 10.3390/antiox12122083.
3
Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response.同时阻断血管内皮生长因子-B（VEGF-B）和白细胞介素-17A（IL-17A）可通过减少异位脂质沉积和减轻炎症反应来改善糖尿病肾病。
Cell Death Discov. 2023 Jan 16;9(1):8. doi: 10.1038/s41420-023-01304-5.
4
Cancer Therapy-Related Hypertension: A Scientific Statement From the American Heart Association.癌症治疗相关高血压：美国心脏协会的科学声明。
Hypertension. 2023 Mar;80(3):e46-e57. doi: 10.1161/HYP.0000000000000224. Epub 2023 Jan 9.
5
Increased Serum VEGF-B Level Is Associated With Renal Function Impairment in Patients With Type 2 Diabetes.血清 VEGF-B 水平升高与 2 型糖尿病患者的肾功能损害有关。
Front Endocrinol (Lausanne). 2022 Mar 24;13:862545. doi: 10.3389/fendo.2022.862545. eCollection 2022.
6
VEGF-B antibody and interleukin-22 fusion protein ameliorates diabetic nephropathy through inhibiting lipid accumulation and inflammatory responses.血管内皮生长因子B抗体与白细胞介素-22融合蛋白通过抑制脂质蓄积和炎症反应改善糖尿病肾病。
Acta Pharm Sin B. 2021 Jan;11(1):127-142. doi: 10.1016/j.apsb.2020.07.002. Epub 2020 Jul 13.
7
VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration.VEGF-B 促进心内膜衍生冠状血管发育和心脏再生。
Circulation. 2021 Jan 5;143(1):65-77. doi: 10.1161/CIRCULATIONAHA.120.050635. Epub 2020 Nov 18.
8
Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease.降低 VEGF-B 信号可改善肾脏脂毒性并预防糖尿病肾病。
Cell Metab. 2017 Mar 7;25(3):713-726. doi: 10.1016/j.cmet.2017.01.004. Epub 2017 Feb 9.
9
Expression of vascular endothelial growth factor (VEGF)-B and its receptor (VEGFR1) in murine heart, lung and kidney.血管内皮生长因子（VEGF）-B及其受体（VEGFR1）在小鼠心脏、肺和肾脏中的表达。
Cell Tissue Res. 2016 Jul;365(1):51-63. doi: 10.1007/s00441-016-2377-y. Epub 2016 Mar 1.
10
VEGF-B: a thing of beauty.血管内皮生长因子-B：一种美妙之物。
Cell Res. 2010 Jul;20(7):741-4. doi: 10.1038/cr.2010.77. Epub 2010 Jun 8.