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腹部创伤手术后改良加速康复外科(ERAS)的实施;可行性和结果评估:一项随机对照试验(RCT)。

Implementation of modified enhanced recovery after surgery (ERAS) following surgery for abdominal trauma; Assessment of feasibility and outcomes: A randomized controlled trial (RCT).

机构信息

Department of General Surgery, Post Graduate Institute of Medical Education and Research, Sector 12, 160012, Chandigarh, India.

Department of General Surgery, Post Graduate Institute of Medical Education and Research, Sector 12, 160012, Chandigarh, India.

出版信息

Am J Surg. 2024 Dec;238:115975. doi: 10.1016/j.amjsurg.2024.115975. Epub 2024 Sep 19.

Abstract

BACKGROUND

Enhanced recovery after surgery(ERAS) is a set of multiple perioperative care component not a rigid protocol with improved outcomes for elective surgeries. This study aimed to assess the feasibility and outcomes in trauma patients undergoing laparotomy.

STUDY DESIGN

Prospective single-centre randomized controlled trial(RCT). Patients undergoing emergency laparotomy following trauma were randomized into ERAS(early removal of catheters, early mobilization and initiation of diet, use of opioid-sparing multimodal analgesia) and conventional care groups 24 ​h post-surgery. Outcome measures included length of hospitalization(LOH), recovery of bowel function, duration of removal of catheters and 30-day complications(Clavien-Dindo).

RESULTS

Fifty patients were randomized into ERAS(n ​= ​25) and conventional care(n ​= ​25) groups. Ninety-two percent of patients were young males, 58 ​% had blunt trauma to the abdomen and the most common indication of surgery was hollow viscus injury(88 ​%). ERAS group had a reduced median LOH(days) (6 versus 8, p ​= ​0.007), early recovery of bowel function(p ​= ​0.010) and shorter times for nasogastric tube(p ​= ​0.001), urinary catheter(p ​= ​0.007) and drain(p ​= ​0.006) removal. The complications were comparable in both groups except for deep surgical site infection[significantly lower in ERAS group(p ​= ​0.009)].

CONCLUSION

ERAS is safe and significantly reduces LOH in select trauma patients undergoing laparotomy.

摘要

背景

术后加速康复(ERAS)是一组围手术期护理措施,而非具有改善择期手术效果的严格方案。本研究旨在评估创伤患者剖腹手术后的可行性和结果。

研究设计

前瞻性单中心随机对照试验(RCT)。创伤后行紧急剖腹手术的患者随机分为 ERAS(早期拔除导管、早期活动和开始饮食、使用阿片类药物节约型多模式镇痛)和常规护理组,术后 24 小时。观察指标包括住院时间(LOH)、肠道功能恢复情况、导管拔除时间和 30 天并发症(Clavien-Dindo)。

结果

50 例患者随机分为 ERAS(n=25)和常规护理组(n=25)。92%的患者为年轻男性,58%有腹部钝性创伤,最常见的手术指征是空腔脏器损伤(88%)。ERAS 组的中位 LOH(天)较短(6 天比 8 天,p=0.007),肠道功能恢复较早(p=0.010),胃管(p=0.001)、尿管(p=0.007)和引流管(p=0.006)拔除时间更短。两组并发症相似,除深部手术部位感染外(ERAS 组明显更低,p=0.009)。

结论

ERAS 安全且可显著缩短选择行剖腹术创伤患者的 LOH。

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